Search for dissertations about: "RDME"

Found 2 swedish dissertations containing the word RDME.

2. 1. Reaction-Diffusion kinetics of Protein DNA Interactions

   Author : Anel Mahmutovic; Johan Elf; David van der Spoel; Pieter Rein ten Wolde; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; umbrella sampling; molecular dynamics; RDME; PDE; sliding; intersegment transfer; hopping; sterics; intersegment transfer; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

   Abstract : Transcription factors need to rapidly find one specific binding site among millions of nonspecific sites on the chromosomal DNA. In this thesis I use various aspects of reaction-diffusion theory to investigate the interaction between proteins and DNA and to explain the searching, finding and binding to specific operator sites. READ MORE

4. 2. Enzymatic activation of oxygen in the biosynthesis of polyketide antibiotics

   Author : Hanna Koskiniemi; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The electron structure of molecular oxygen (O2) is such that it cannot spontaneously react with organic molecules, a feature that protects organisms from oxidative stress. However, oxygenases can insert O2 in organic substrates. The enzymes do this after activating O2 for the reaction, most often with the aid of an organic or inorganic cofactor. READ MORE