Search for dissertations about: "RETROVIRUS"
Showing result 1 - 5 of 45 swedish dissertations containing the word RETROVIRUS.
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1. Reverse Transcriptase Activity Assays for Retrovirus Quantitation and Characterization
Abstract : Reverse transcriptase (RT) is a crucial enzyme for retrovirus replication, and its presence in the virion is indispensable for infectivity. This thesis illustrates the use of RT activity assays as tools for quantitation and characterization of different retroviruses, particularly HIV. READ MORE
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2. On the etiology and pathogenesis of systemic lupus erythematosus with special reference to environmental factors
Abstract : Systemic lupus erythematosus (SLE) is a complex autoimmune disease in which environmental factors interact with genetic factors in the development of the disease process and evolution of clinical manifestations. In this thesis both exogenous factors and host factors were investigated, as well as important immunopathological aspects including involvement of immune complex (IC), the complement system and interferon-alpha (IFN-α). READ MORE
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3. Viral dUTPases, Recombinant Expression, Purification and Characterization
Abstract : The enzyme deoxyuridine 5’-triphosphate nucleotidohydrolase (dUTPase, EC 3.6.1.23) catalyzes the hydrolysis of dUTP to dUMP and pyrophosphate. READ MORE
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4. On Monomeric and Trimeric dUTPases. Recombinant Expression, Purification, Conformational Properties and Catalytic Characteristics
Abstract : Nucleotide metabolism and replication of nucleic acids are processes of fundamental importance. A crucial enzyme in nucleotide metabolism is dUTPase (E.C. 3. READ MORE
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5. Retroviral long Terminal Repeats; Structure, Detection and Phylogeny
Abstract : Long terminal repeats (LTRs) are non-coding repeats flanking the protein-coding genes of LTR retrotransposons. The variability of LTRs poses a challenge in studying them. Hidden Markov models (HMMs), probabilistic models widely used in pattern recognition, are useful in dealing with this variability. READ MORE