Search for dissertations about: "RNA Pol II"

Showing result 1 - 5 of 33 swedish dissertations containing the words RNA Pol II.

2. 1. Non-protein-coding RNA : Transcription and regulation of ribosomal RNA

   Author : Stefanie Böhm; Ann-Kristin Östlund Farrants; Brian McStay; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; ribosomal RNA; non-coding RNA; ribosomal genes; rDNA gene; B-WICH; chromatin remodelling; histone modification; Cell Biology; cellbiologi;

   Abstract : Cell growth and proliferation are processes in the cell that must be tightly regulated. Transcription of ribosomal RNA and ribosomal biogenesis are directly linked to cell growth and proliferation, since the ribosomal RNA encodes for the majority of transcription in a cell and ribosomal biogenesis influences directly the number of proteins that are synthesized. READ MORE

4. 2. RNA Polymerase I regulation by chromatin remodelling

   Author : Yuan Guo; Ann-Kristin Östlund Farrants; Marikki Laiho; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; RNA Pol I; ribosome genes; chromatin remodelling; WSTF; CHD4; molekylär biovetenskap; Molecular Bioscience;

   Abstract : Cell proliferation and growth is correlated with effective protein synthesis and ribosome biogenesis. The transcription of the 47S pre-ribosomal RNA by RNA Polymerase I (RNA Pol I) machinery is the rate-limiting step of ribosome biogenesis and can accounts for more than 50% of total cellular transcription. READ MORE

5. 3. Functional Characterization of the Cellular Protein p32 : A Protein Regulating Adenovirus Transcription and Splicing Through Targeting of Phosphorylation

   Author : Christina Öhrmalm; Göran Akusjärvi; Neus Visa; Uppsala universitet; []
   Keywords : Cell and molecular biology; Adenovirus; p32; ASF SF2; E4-ORF4; Splicing; Transcription; CTD; RNA Pol II; Cell- och molekylärbiologi;

   Abstract : Cellular processes involved in the conversion of the genetic information from DNA into a protein are often regulated by reversible phosphorylation reactions. By modulating the phosphorylated status of key proteins their activity can either be enhanced or repressed. READ MORE

6. 4. Functional studies of Mediator in Arabidopsis thaliana and Saccharomyces cerevisiae

   Author : Nils Elfving; Stefan Björklund; Jesper Svejstrup; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transcriptional regulation; chromatin; stress; Pol II; mediator; DREB2A; ZFHD1; MYB-like; Msn2; molekylärbiologi; Molecular Biology;

   Abstract : Mediator has been shown to be essential for regulation of RNA Polymerase II mediated transcription. Mediator functions as an interface between the general transcriptional machinery and a multitude of DNA binding transcriptional regulators, although the molecular mechanism for the process is elusive. READ MORE

7. 5. Studies of Functional Interactions within Yeast Mediator and a Proposed Novel Mechanism for Regulation of Gene Expression

   Author : Magnus Hallberg; Stefan Björklund; Karl Ekwall; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Mediator; Transcriptional regulation; Srb10; Cdk8; Med2; Srb7; Med21; RNA pol II; Biokemi; Biochemistry; Biokemi; medicinsk biokemi; Medical Biochemistry;

   Abstract : The yeast Mediator complex is required for transcriptional regulation both in vivo and in vitro and the identification of similar complexes from metazoans indicates that its function is conserved through evolution. Mediator subunit composition and structure is well characterized both by biochemical, genetic and biophysical methods. READ MORE