Search for dissertations about: "RNA chaperone"
Showing result 1 - 5 of 16 swedish dissertations containing the words RNA chaperone.
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1. The interactome of the Epstein-Barr virus nuclear antigen 5 suggests novel roles in RNA and protein metabolism
Abstract : Epstein-Barr virus (EBV) is a human herpes virus that infects B and epithelial cells of the oropharynx. EBV is transmitted by saliva and establishes a lifelong latency in over 90% of the world's population. During latency, the virus exists predominantly as multicopy episomes in the nuclei of memory B cells. READ MORE
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2. Study on the Function of Translation Initiation Factor IF1
Abstract : Initiation is the first step in protein biosynthesis representing a fundamental event in cell life which determines fidelity, efficiency and regulation of gene expression. In addition to the ribosome and mRNA, three protein factors IF1, IF2 and IF3 are involved in the initiation of translation in prokaryotes. READ MORE
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3. Functional characterization of the small antisense RNA MicA in Escherichia coli
Abstract : The Escherichia coli small RNA (sRNA) MicA was identified recently in a genomewide search for sRNAs. It is encoded between the genes gshA and luxS in E. coli and its close relatives. The function of sRNAs in bacteria is generally believed to be in maintenance of homeostasis via stress-induced modulation of gene expression. READ MORE
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4. Small RNAs, Big Consequences : Post-transcriptional Regulation and Adaptive Immunity in Bacteria
Abstract : It is nowadays widely accepted that non-coding RNAs play important roles in post-transcriptional regulation of genes in all kingdoms of life. In bacteria, the largest group of RNA regulators are the small RNAs (sRNAs). READ MORE
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5. Advancing antiviral strategies against emerging RNA viruses by phenotypic drug discovery
Abstract : Pathogenic RNA viruses can emerge from unexpected sources at unexpected times and cause severe disease in humans, as exemplified by the ongoing coronavirus disease 19 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and Ebola virus (EBOV), Crimean-Congo hemorrhagic fever virus (CCHFV) and Zika virus (ZIKV) outbreaks from the past decade. Despite the increasing impact of emerging viruses to health and economy worldwide, our preparedness to stand against these diseases is hampered by the lack of approved and effective antiviral therapies. READ MORE