Search for dissertations about: "RNA removal"

Showing result 1 - 5 of 33 swedish dissertations containing the words RNA removal.

  2. 1. Molecular insights into primer removal during mtDNA replication

    Author : Ali Al-Behadili; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mitochondria; Mitochondrial DNA replication; DNA replication; Primer removal; RNase H1; Primer formation; Replication initiation; mitochondrial diseases;

    Abstract : Mitochondria are vital for cell survival, and the primary producers of ATP, the energy currency used for various metabolic processes. Mitochondria are unique from other cellular compartments because they have their own genomes of circular small double-stranded DNA (mtDNA) of approximately 16. READ MORE

  4. 2. Removal and Replacement of Ribosomal Proteins : Effects on Bacterial Fitness and Ribosome Function

    Author : Christina Tobin; Dan I. Andersson; Richard Buckingham; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ribosome; protein synthesis; ribosomal proteins; translation initiation; ribosome biogenesis; fitness costs; compensatory evolution; horizontal gene transfer; Microbiology; Mikrobiologi; Biochemistry; Biokemi; Mikrobiologi; Microbiology;

    Abstract : Protein synthesis is a complex process performed by sophisticated cellular particles known as ribosomes. Although RNA constitutes the major structural and functional component, ribosomes from all kingdoms contain an extensive array of proteins with largely undefined functional roles. READ MORE

  5. 3. An RNA story, from chromatin to protein

    Author : Davide Maria Trevisan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : RNA functions expand well over just coding for protein effectors. Non-coding RNAs oversee translation, RNA processing, and spatial organization of the cellular space, therefore participating in the regulation of almost any cellular process. To add a further layer of complexity, both coding and non-coding RNAs are extensively modified. READ MORE

  6. 4. Metal ion cooperativity in Escherichia coli RNase P RNA

    Author : Mathias Brännvall; Britt-Marie Sjöberg; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; RNase P; divalent metal ions; substrate interaction; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; mikrobiologi; Microbiology;

    Abstract : RNase P is an essential ribonuclease responsible for removal of the 5’ leader of tRNA precursors. Bacterial RNase P consists of an RNA subunit and a small basic protein. The catalytic activity is associated with the RNA subunit, i.e. READ MORE

  7. 5. Small Cajal body-associated RNA 2 and RNA-binding protein WRAP53β in DNA repair and Hoyeraal-Hreidarsson syndrome

    Author : Sofie Bergstrand; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The DNA in our cells can be damaged through many different mechanisms and correct repair of DNA lesions is of utmost importance to ensure genomic integrity and prevent alteration in the genetic code contributing to diseases such as cancer, neurodegenerative disorders and premature aging. Non-coding RNAs were for a long time considered as non-functional transcriptional byproducts. READ MORE