Search for dissertations about: "RNA-Sequencing"
Showing result 11 - 15 of 270 swedish dissertations containing the word RNA-Sequencing.
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11. Spatially resolved and single cell transcriptomics
Abstract : In recent years, massive parallel sequencing has revolutionized the field of biology and has provided us with a vast number of new discoveries in fields such as neurology, developmental biology and cancer research. A significant area is deciphering gene expression patterns, as well as other aspects of transcriptome information, such as the impact of splice variants and mutations on biological functions and disease development. READ MORE
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12. Genome-wide Characterization of RNA Expression and Processing
Abstract : The production of fully mature protein-coding transcripts is an intricate process that involves numerous regulation steps. The complexity of these steps provides the means for multilayered control of gene expression. READ MORE
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13. Spatially Resolved Gene Expression Analysis
Abstract : Spatially resolved transcriptomics has greatly expanded our knowledge of complex multicellular biological systems. To date, several technologies have been developed that combine gene expression data with information about its spatial tissue context. READ MORE
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14. Functional characteristics of periodontitis and peri-implantitis lesions in humans
Abstract : In the current series of studies functional characteristics of periodontitis and peri-implantitis lesions in humans were investigated. Cell markers for antimicrobial activity were used to evaluate differences between periodontitis and peri-implantitis lesions (Study I), while epigenetic and oxidative stress markers were used to compare periodontitis lesions in smokers and non-smokers (Study II). READ MORE
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15. Multifaceted RNA-mediated regulatory mechanisms in Streptococcus pyogenes
Abstract : Bacterial pathogens rely on precise regulation of gene expression to coordinate host infection processes and resist invasion by mobile genetic elements. An interconnected network of protein and RNA regulators dynamically controls the expression of virulence factors using a variety of mechanisms. READ MORE