Search for dissertations about: "RNA-Sequencing"

Showing result 21 - 25 of 272 swedish dissertations containing the word RNA-Sequencing.

  2. 21. The Spatial Context – through the lens of method development

    Author : Linda Kvastad; Joakim Lundeberg; Lars Feuk; KTH; []
    Keywords : RNA; RNA-sequencing; transcriptomics; spatial transcriptomics; single cells; pediatric brain tumors; Spatial RIN; Bioteknologi; Biotechnology;

    Abstract : In the present moment of time, we find ourselves in a period where the advancement of genomic tools is progressing at a fast pace. Of particular interest for this thesis is the study of gene activity. READ MORE

  4. 22. Towards spatial host-microbiome profiling

    Author : Britta Lötstedt; Joakim Lundeberg; Petri Auvinen; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; 16S sequencing; RNA sequencing; spatially resolved transcriptomics; antibody-based measurements; Bioteknologi; Biotechnology;

    Abstract : Sequencing technologies and applications have pushed the limits and enabled novel studies of biological mechanisms, evolutionary relationships and communication networks between cells. The technical developments leading to single cell RNA-sequencing have enabled detection of rare cell populations while spatial resolution added insights into larger biological environments, like tissues and organs. READ MORE

  5. 23. Metabolic Engineering of Central Carbon Metabolism in Saccharomyces cerevisiae The contribution of systems biology to physiological studies

    Author : Marta Papini; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; fermentation technology; Metabolic engineering; RNA-sequencing; Saccharomyces cerevisiae; DNA microarrays; 13Cbased flux analysis; system biology; Scheffersomyces stipitis;

    Abstract : Saccharomyces cerevisiae is one of the most well characterized yeast of large industrial interest due to several attractivefeatures such as its capability to efficiently convert glucose into ethanol and carbon dioxide at high flux, its amenabilityto genetic modification and the presence of extensive knowledge databases. For these reasons, it is often considered asuitable cell factory for the production of different classes of compounds. READ MORE

  6. 24. Endocrine disruption in fish : Effects of 17α-ethinylestradiol exposure on non-reproductive behavior, fertility and brain and testis transcriptome

    Author : Tove Porseryd; Inger Porsch Hällström; Ioanna Katsiadaki; Södertörns högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; 17α-ethinylestradiol; endocrine disrupting chemical; fish; behavior; fertility; transcriptome; RNA sequencing; Environmental Studies; Miljövetenskapliga studier; Östersjö- och Östeuropaforskning; Baltic and East European studies;

    Abstract : Aquatic environments are the end recipient for most anthropogenic chemical pollutants. One common chemical pollutant found in the aquatic environment is 17α-ethinylestradiol (EE2), a synthetic estrogen used in contraceptive pills. READ MORE

  7. 25. Interpreting the human transcriptome

    Author : Beata Werne Solnestam; Joakim Lundeberg; Piero Carninci; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transcriptome; RNA sequencing; high-throughput sequencing; gene expression profiling; multiplex amplification; Bioteknologi; Biotechnology;

    Abstract : The human body is made of billions of cells and nearly all have the same genome. However, there is a high diversity of cells, resulted from what part of the genome the cells use, i.e. which RNA molecules are expressed. READ MORE