Search for dissertations about: "RNA-seq"

Showing result 1 - 5 of 71 swedish dissertations containing the word RNA-seq.

  1. 1. Integration of RNA and protein expression profiles to study human cells

    Author : Frida Danielsson; Emma Lundberg; Mikael Huss; Mathias Uhlén; Christine Vogel; KTH; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; RNA-seq; Transcriptomics; Proteomics; Malignant transformation; Cancer; Functional enrichment; Biotechnology; Bioteknologi; Medicinsk teknologi; Medical Technology;

    Abstract : Cellular life is highly complex. In order to expand our understanding of the workings of human cells, in particular in the context of health and disease, detailed knowledge about the underlying molecular systems is needed. READ MORE

  2. 2. Persistent infection by Yersinia pseudotuberculosis

    Author : Kemal Avican; Maria Fällman; Wyndham W. Lathem; Umeå universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Persistent infection; RNA-seq; PMNs; Yersinia; Transcriptome; wrba; fnr; rovA; arcA; rfaH; molekylärbiologi; Molecular Biology; Infectious Diseases; infektionssjukdomar; immunologi; Immunology;

    Abstract : Enteropathogenic Yersinia species can infect many mammalian organs such as the small intestine, cecum, Peyer’s patches, liver, spleen, and lung and cause diseases that resemble a typhoid-like syndrome, as seen for other enteropathogens. We found that sublethal infection doses of Y. READ MORE

  3. 3. Computational methods for analysis and visualization of spatially resolved transcriptomes

    Author : Jose Fernandez Navarro; Joakim Lundeberg; Martin Hemberg; KTH; []
    Keywords : RNA; RNA-seq; single cell; scRNA-seq; transcriptomics; spatial transcriptomics; brain; 3D; Alzheimer’s disease; Biotechnology; Bioteknologi;

    Abstract : Characterizing the expression level of genes (transcriptome) in cells and tis- sues is essential for understanding the biological processes of multicellular or- ganisms. RNA sequencing (RNA-seq) has gained traction in the last decade as a powerful tool that provides an accurate quantitative representation of the transcriptome in tissues. READ MORE

  4. 4. Sex, Molecules, and Gene control : Ecophysiological and evolutionary aspects of key sponge species from Antarctic shallow waters and the deep sea

    Author : Vasiliki Koutsouveli; Paco Cárdenas; Anders Backlund; Ana Riesgo; Cassandra G. Extavour; Uppsala universitet; []
    Keywords : Porifera; Demospongiae; Geodia spp.; Phakellia ventilabrum; reproduction; gametogenesis; Antarctica; deep sea; sponge grounds; histology; molecular machinery; electron microscopy; RNA-seq; proteomics; lipidomics; Farmakognosi; Pharmacognosy;

    Abstract : Very little is known about the ecophysiological aspects of Porifera (sponges) from Antarctica and North Atlantic, even though they are keystone components of these habitats. Being the earliest diverging metazoan lineage, sponges also play a fundamental role in our understanding of animal evolution. READ MORE

  5. 5. Development and Application of Genomic Resources in Non-model Bird Species

    Author : Biao Wang; Jacob Höglund; Christopher Wheat; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; genome; transcriptome; next generation sequencing; non-model species; bioinformatics; reference guided assembly; RNA-Seq; comparative genomics; gene expression; major histocompatibility complex; single nucleotide polymorphism; microsatellite; Biologi; Biology;

    Abstract : Understanding the genetic basis of biological processes is a fundamental component of modern ecology and evolutionary biology studies. With the recent advent of next generation sequencing (NGS) technologies, it is now possible to perform large genome and transcriptome projects for ecologically important non-model species. READ MORE