Search for dissertations about: "RTK"
Showing result 11 - 15 of 45 swedish dissertations containing the word RTK.
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11. On the Multi-Scale Nature of Ski-Snow Friction : Field Testing, Characterisation and Modelling of Cross-Country Ski Performance
Abstract : The goal of most endurance sports is to get from point A to B in the shortest time possible. Throughout the course, athletes need to overcome the resistive forces that are present in their specific sport. READ MORE
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12. Reciprocal regulation of endocytosis and signaling in Drosophila epithelial development and aberrant growth
Abstract : Endocytosis and subsequent endosomal sorting of plasma membrane proteins and nutrients are essential for cellular homeostasis. Previous work has uncovered several different internalization mechanisms, endosomal sorting routes and aspects of their regulation. READ MORE
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13. Cell fate specification by Ras-mediated cell signalling in C. elegans
Abstract : Induction of vulval fates in the C. elegans hermaphrodite is mediated by a conserved RTK/Ras/MAP kinase signalling pathway, in which the core components can be placed into a linear genetic and biochemical pathway. However, the events that occur downstream of this pathway are not yet well understood. READ MORE
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14. Exploiting Drosophila as a model system for studying anaplastic lymphoma kinase in vivo
Abstract : Anaplastic Lymphoma Kinase (ALK) is a Receptor Tyrosine Kinase (RTK) and an oncogene associated with several human diseases, but its normal function in humans and other vertebrates is unclear. Drosophila melanogaster has an ALK homolog, demonstrating that the RTK has been conserved throughout evolution. READ MORE
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15. Ubiquitination and Receptor Endocytosis
Abstract : Protein ubiquitination is an evolutionary conserved mechanism that controls a wide variety of cellular functions. Polyubiquitinated proteins are generally degraded in the proteasome, whereas monoubiquitination controls various other cellular processes, including endocytosis and endosomal sorting. READ MORE