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Showing result 1 - 5 of 398 swedish dissertations matching the above criteria.
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1. Cellular effects of ionizing radiation : Relevant for understanding cancer risk after medical and environmental radiation exposures
Abstract : Radiation-induced cancers are stochastic and delayed effects of exposure to ionizing radiation. The dose-response relationship for radiation-induced cancers at both low dose/low dose rates and high doses (doses encountered during radiotherapy) remains unclear. READ MORE
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2. Dose painting : Can radiotherapy be improved with image driven dose-responses derived from retrospective radiotherapy data?
Abstract : The main aim of curative radiotherapy for cancer is to prescribe and deliver doses that eradicate the tumor and spare the normal healthy tissues. Radiotherapy is commonly performed by delivering a homogeneous radiation dose to the tumor. READ MORE
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3. Biomarkers of ionising radiation relevant to carcinogenesis : Dose, dose rate and LET dependency of the responses
Abstract : A better understanding of the relationship between ionising radiation (IR) dose, dose rate and radiation quality, and the risk of stochastic effects would improve risk extrapolation from atomic bomb survivors’ data. Owing to insufficient statistical power of epidemiological studies to detect excess incidence of cancer following low doses of IR delivered at low dose rates (LDLDR), as typically encountered in most common human exposure scenarios, radiobiological experiments are fundamental to describe the biological effectiveness of LDLDR and to define the underlying molecular mechanisms. READ MORE
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4. Energy and intensity modulated radiation therapy with electrons
Abstract : In recent years intensity modulated radiation therapy with photons (xIMRT) has gained attention due to its ability to reduce the dose in the tissues close to the tumour volume. However, this technique also results in a large low dose volume. READ MORE
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5. The microdosimetric variance-covariance method used for beam quality characterization in radiation protection and radiation therapy
Abstract : Radiation quality is described by the RBE (relative biological effectiveness) that varies with the ionizing ability of the radiation. Microdosimetric quantities describe distributions of energy imparted to small volumes and can be related to RBE. READ MORE