Search for dissertations about: "Radiation effects"

Showing result 1 - 5 of 581 swedish dissertations containing the words Radiation effects.

  2. 1. Cellular effects of ionizing radiation : Relevant for understanding cancer risk after medical and environmental radiation exposures

    Author : Pamela Chiaka Akuwudike; Andrzej Wojcik; Lovisa Lundholm; Kerstin Borgmann; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiation; DNA damage; radiation-induced carcinogenesis; second primary cancer; cisplatin chemoradiotherapy; dose fractionation; low dose; low dose rate; dose and dose rate effectiveness factor DDREF ; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Radiation-induced cancers are stochastic and delayed effects of exposure to ionizing radiation. The dose-response relationship for radiation-induced cancers at both low dose/low dose rates and high doses (doses encountered during radiotherapy) remains unclear. READ MORE

  4. 2. Colorectal cancer and radiation response : The role of EGFR, AKT and cancer stem cell markers

    Author : Sara Häggblad Sahlberg; Bo Stenerlöw; Bengt Glimelius; Marika Nestor; Torgny Stigbrand; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; colorectal cancer; radiation; AKT; EGFR; cancer stem cells; CD133; CD44; Biomedical Radiation Science; Biomedicinsk strålningsvetenskap; Biologi med inriktning mot molekylär cellbiologi; Biology with specialization in Molecular Cell Biology;

    Abstract : The primary treatment for colorectal cancer is surgery. Radiotherapy and chemotherapy, sometimes combined, are also frequently used to diminish recurrence risk. In response to radiation exposure, several cellular signaling cascades are activated to repair DNA breaks, prevent apoptosis and to keep the cells proliferating. READ MORE

  5. 3. Role of MTH1 and MYH proteins in genotoxic effects of radiation

    Author : Sara Shakeri Manesh; Siamak Haghdoost; William F. Morgan; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MTH1; MYH; gamma radiation; UV radiation; oxidative stress; low dose rate ionizing radiation; molekylärgenetik; Molecular Genetics;

    Abstract : Humans are constantly exposed to different types of radiations. It has been suggested that low dose and low dose rate of γ-radiation as well as ultra violet A (UVA) induce oxidative stress in cells that may promote mutations. READ MORE

  6. 4. Radiation induced biomarkers of individual sensitivity to radiation therapy

    Author : Sara Skiöld; Mats Harms-Ringdahl; Siamak Haghdoost; Mats Ljungman; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; low dose ionizing radiation; radiation sensitivity; proteomics; whole blood; 8-oxo-dG; oxidative stress; acute adverse healthy tissue effects; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Fifty percent of solid cancers are treated with radiation therapy (RT). The dose used in RT is adjusted to the most sensitive individuals so that not more than 5% of the patients will have severe adverse healthy tissue effects. READ MORE

  7. 5. Ethical aspects of radiation protection

    Author : Per Wikman-Svahn; John Cantwell; Gustaf Arrhenius; KTH; []
    Keywords : HUMANIORA; HUMANITIES; Radiation; risk; ethics; Philosophy subjects; Filosofiämnen;

    Abstract : This aim of this thesis is to examine ethical aspects of radiation protection from ionizing radiation. Radiation protection is the professional field that deals with the protection of humans and the environment from the harmful effects of radiation. READ MORE