Search for dissertations about: "Radiotherapy and medical oncology"

Showing result 1 - 5 of 136 swedish dissertations containing the words Radiotherapy and medical oncology.

  2. 1. Radiotherapy for head and neck cancer : costs and benefits of time, dose and volume

    Author : Karin Söderström; Björn Zackrisson; Werner Dubrowsky; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radiotherapy; head and neck cancer; adjuvant treatment; accelerated fractionation; biomedicinsk strålningsvetenskap; Biomedical Radiation Science;

    Abstract : Background In the treatment of head and neck cancers (HNCs), radiotherapy (RT) has the advantage of organ preservation compared to surgery. However, treatment toxicities associated with RT can affect important functions for everyday life, both in the acute and late stage. READ MORE

  4. 2. Glioblastoma heterogeneity and plasticity : Investigating the roles of BMP4 and SOX2

    Author : Erika Dalmo; Bengt Westermark; Fredrik J. Swartling; Lene Uhrbom; Ana Martin-Villalba; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioblastoma; SOX2; BMP4; senescence; plasticity; Oncology; Onkologi; Medicinsk vetenskap; Medical Science; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Abstract : The malignant primary brain tumor glioblastoma has a dismal prognosis and is distinguished by its heterogeneous character. Current treatment with surgical resection, radiotherapy and adjuvant chemotherapy with the alkylating agent temozolomide does not provide a cure, but simply prolongs survival by a few months. READ MORE

  5. 3. New Molecular Approaches to Glioblastoma Therapy

    Author : Sathishkumar Baskaran; Sven Nelander; Karin Forsberg Nilsson; Silvia Marino; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioblastoma; GBM; ZBTB16; PLZF; Heterogeneity; Proteasome inhibitors; Bortezomib; Pterostilbene; drug combinations; Oncology; Onkologi; Biological Research on Drug Dependence; Biologisk beroendeforskning; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Biomedical Laboratory Science; Biomedicinsk laboratorievetenskap; Medicinsk vetenskap; Medical Science; Molekylär medicin; Molecular Medicine;

    Abstract : Glioblastoma (GBM) is the most common high-grade brain tumor diagnosed in patients who are more than 50 years of age. The standard of care treatment is surgery, followed by radiotherapy and chemotherapy. The median life expectancy of patients is only between 12 to 15 months after receiving current treatment regimes. READ MORE

  6. 4. Clinical application of intensity and energy modulated radiotherapy with photon and electron beams

    Author : Xiangkui Mu; Björn Zackrisson; Mikael Karlsson; Thomas Björk-Eriksson; Erik Blomquist; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Radiotherapy; IMXT; IMET; IMPT; proton beams; electron beams; treatment planning; cancer induction; side-effects; fraction time; intensity modulated radiotherapy; Onkologi; Oncology; Onkologi; Oncology; onkologi;

    Abstract : In modern, advanced radiotherapy (e.g. intensity modulated photon radiotherapy, IMXT) the delivery time for each fraction becomes prolonged to 10-20 minutes compared with the conventional, commonly 2-5 minutes. The biological effect of this prolongation is not fully known. READ MORE

  7. 5. Patient experiences of the radiotherapy process and treatment

    Author : Kristina Olausson; Björn Zackrisson; Lena Sharp; Ulrika Östlund; Birgitta Johansson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; radiotherapy; radiation skin reactions; patient experience; treatment environment; anxiety; person-centred care; questionnaire.; onkologi; Oncology;

    Abstract : BackgroundMost cancer patients undergo external radiotherapy (RT) at some stage during their treatment trajectory. RT is often associated with unfamiliar procedures where the technical environment, side effects and interaction with staff seem to play a major role in the patient’s treatment experience. READ MORE