Advanced search

Showing result 1 - 5 of 17 swedish dissertations matching the above criteria.

2. 1. Clinical application of intensity and energy modulated radiotherapy with photon and electron beams

   Author : Xiangkui Mu; Björn Zackrisson; Mikael Karlsson; Thomas Björk-Eriksson; Erik Blomquist; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Radiotherapy; IMXT; IMET; IMPT; proton beams; electron beams; treatment planning; cancer induction; side-effects; fraction time; intensity modulated radiotherapy; Onkologi; Oncology; Onkologi; Oncology; onkologi;

   Abstract : In modern, advanced radiotherapy (e.g. intensity modulated photon radiotherapy, IMXT) the delivery time for each fraction becomes prolonged to 10-20 minutes compared with the conventional, commonly 2-5 minutes. The biological effect of this prolongation is not fully known. READ MORE

4. 2. Childhood malignant disease and consequences for growth hormone secretion, intellectual function and cardiovascular risk

   Author : Katarina Link; Lund Medicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Growth hormone deficiency; Insulin sensitivity; Cranial radiotherapy; Neuropsychological performance; Endocrinology; secreting systems; diabetology; Acute Lymphoblastic leukemia; diabetologi; sekretion; Endokrinologi;

   Abstract : In childhood onset growth hormone deficiency (GHD) a reduction in cardiac left ventricular mass (LVMi) and impairment of cardiac systolic function, as well as in glomerular filtration rate (GFR) has been shown. In study I, we showed that a low dose of GH treatment for 10 months resulted in increased LVMi and kidney size. READ MORE

5. 3. Long-term Morbidity and Socioeconomic Outcome among Nordic Childhood Cancer Survivors

   Author : Anna Sällfors-Holmqvist; Lund Pediatrik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Childhood cancer survivors; late complications; morbidity; late socioeconomic effects;

   Abstract : Survival after childhood cancer has improved dramatically during the past four decades, resulting in a five-year survival rate of 80% in children recently treated for cancer in the Nordic countries. However, these advances in treatment and survival has come at a price, and many survivors face significant treatment-induced sequelae, most of which only become clinically apparent many years after the child has been cured. READ MORE

6. 4. Late complications of childhood acute lymphoblastic leukaemia (ALL), with special reference to hormone secretion, cardiovascular risk and bone health

   Author : Cecilia Follin; Lund Medicin; []
   Keywords : growth hormone treatment; growth hormone deficiency; cranial radiotherapy; Acute lymphoblastic leukaemia; cardiovascular risk factors; bone mineral density; prolactininsufficiency;

   Abstract : An increased prevalence of cardiovascular (CV) risk factors and cardiac abnormalities has been shown among adult GH deficient ALL survivors subjected to cranial irradiation. The ALL treatment includes many known risk factors for low bone mineral density (BMD), but little is known about pituitary insufficiencies, except for GH deficiency. READ MORE

7. 5. Childhood acute lymphoblastic leukaemia. Late effects in young adult survivors

   Author : Marianne Jarfelt; Göteborgs universitet; []
   Keywords : childhood acute lymphoblastic leukaemia; adult survivor; GH secretion; body composition; bone mineral density; exercise echocardiography;

   Abstract : Acute lymphoblastic leukaemia (ALL) is the most common malignancy in children. The 5-year survival rate has gradually increased from 5% in early 1970s to over 80% today. Until now most patients have been discharged from further follow up after puberty. READ MORE