Search for dissertations about: "Radu Vasilcanu"

Found 1 swedish dissertation containing the words Radu Vasilcanu.

2. 1. Regulation of insulin-like growth factor-1 receptor expression and signaling

   Author : Radu Vasilcanu; Karolinska Institutet; Karolinska Institutet; []
   Keywords : IGF-1R; â-arrestins; MDM2; ubiquitination; internalization;

   Abstract : Insulin-like growth factor-1 receptor (IGF-1R), a member of the insulin receptor tyrosine kinase family is a broadly expressed transmembrane receptor that plays a key role in malignant cell growth. IGF-1R transmits information provided by extracellular stimuli into intracellular signaling pathways resulting in the subsequent regulation of various effector systems. READ MORE