Advanced search
Showing result 1 - 5 of 36 swedish dissertations matching the above criteria.
-
1. Applied bioinformatics for gene characterization
Abstract : As the vast majority of human protein-encoding genes are now identified, the new challenge placed before life scientists is the determination of the functions of the proteins. Traditionally, intense, directed efforts are applied to decipher the function of a novel protein using laboratory techniques. READ MORE
-
2. Krylov methods for nonlinear eigenvalue problems and matrix equations
Abstract : Nonlinear eigenvalue problems (NEPs) arise in many fields of science and engineering. Such problems are often defined by large matrices, which have specific structures, such as being sparse, low-rank, etc. Like the linear eigenvalue problem, the eigenvector appears in a linear form, whereas the eigenvalue appears in a nonlinear form. READ MORE
-
3. Affinity protein based inhibition of cancer related signaling pathways
Abstract : Dysregulation of protein activity, caused by alterations in protein sequence, expression, or localization, is associated with numerous diseases. In order to control the activity of harmful protein entities, affinity ligands such as proteins, oligonucleotides or small molecules can be engineered to specifically interact with them to modulate their function. READ MORE
-
4. Ribosome display for selection and evolution of affibody molecules
Abstract : Affinity proteins are invaluable tools in biotechnological and medical applications. This thesis is about combinatorial protein engineering principles for the generation of novel affinity proteins to purify mouse immunoglobulin, detect a potential cancer marker protein or inhibit a cell proliferation pathway. READ MORE
-
5. The Effects of SSRI Treatment on Human Placenta and Embryo
Abstract : During pregnancy, 4 - 7% of women suffer from major depressive disorder. When antidepressive treatment is needed, selective serotonin reuptake inhibitors (SSRIs) are the most commonly used. Although severe complications from SSRI treatment are rare, association with a number of adverse pregnancy and fetal outcomes has been found. READ MORE