Search for dissertations about: "Ramon Grima"

Found 2 swedish dissertations containing the words Ramon Grima.

  2. 1. Stochastic Simulation of Multiscale Reaction-Diffusion Models via First Exit Times

    Author : Lina Meinecke; Per Lötstedt; Stefan Engblom; Ramon Grima; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; computational systems biology; diffusion; first exit times; unstructured meshes; reaction-diffusion master equation; macromolecular crowding; excluded volume effects; finite element method; backward analysis; stochastic simulation; Beräkningsvetenskap med inriktning mot numerisk analys; Scientific Computing with specialization in Numerical Analysis;

    Abstract : Mathematical models are important tools in systems biology, since the regulatory networks in biological cells are too complicated to understand by biological experiments alone. Analytical solutions can be derived only for the simplest models and numerical simulations are necessary in most cases to evaluate the models and their properties and to compare them with measured data. READ MORE

  4. 2. Large-scale simulation-based experiments with stochastic models using machine learning-assisted approaches : Applications in systems biology using Markov jump processes

    Author : Fredrik Wrede; Andreas Hellander; Ramon Grima; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; bioinformatics; systems biology; stochastic simulation; model exploration; approximate parameter inference; machine learning; distributed computing; Beräkningsvetenskap; Scientific Computing;

    Abstract : Discrete and stochastic models in systems biology, such as biochemical reaction networks, can be modeled as Markov jump processes. The chemical master equation describes how the probability distribution of a biochemical system's states evolves. Unfortunately, solutions to the chemical master equation only exist for trivial problems. READ MORE