Search for dissertations about: "Rap GTPases"
Found 4 swedish dissertations containing the words Rap GTPases.
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1. Exoenzyme S of Pseudomonas aeruginosa : cellular targets and interaction with 14-3-3
Abstract : Pseudomonas aeruginosa is an opportunistic pathogen that is a serious problem for immuno-compromised patients. Toxins such as exoenzyme (Exo) S, ExoT, ExoY and ExoU are secreted and translocated from the bacteria into the eukaryotic cell via the bacterial encoded type III secretion system. READ MORE
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2. Epac2 signaling at the β-cell plasma membrane
Abstract : Secretion of appropriate amounts of insulin from pancreatic β-cells is crucial for glucose homeostasis. The β-cells release insulin in response to glucose and other nutrients, hormones and neurotransmitters, which trigger intracellular signaling cascades, that result in exocytotic fusion of insulin-containing vesicles with the plasma membrane. READ MORE
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3. Glucosyltransferase toxins from clostridia : molecular interactions with cells
Abstract : An enzymatic activity was recently described for the group of Large Clostridial Cytotoxins (LCTs). This activity is glucosyltransfer and consists in the covalent addition of glucose, from UDP-glucose (UDP-Glc) to threonine 35 of small GTPases of the Rho subfamily. READ MORE
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4. Changes in neuronal properties induced by neurotropic infections
Abstract : The nervous system can be the target for various bacterial and viral infectious agents. Certain bacterial toxins have been found to impair specific proteins, such as proteins involved in transmitter release and in the regulation of the cytoskeleton. READ MORE