Search for dissertations about: "Ras superfamily"

Found 2 swedish dissertations containing the words Ras superfamily.

  1. 1. Cellular targets of Pseudomonas aeruginosa toxin Exoenzyme S

    Author : Maria Henriksson; Bengt Hallberg; Lars Rönnstrand; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Pseudomonas aeruginosa; ADP-ribosylation; GAP; Ras superfamily; NAD; ExoS; 14-3-3; Cellbiologi; Cell biology; Cellbiologi; molecular cell biology; molekylär cellbiologi;

    Abstract : Pseudomonas aeruginosa is an opportunistic pathogen that can cause life-threatening infections in immunocompromised patients. It uses a type III secretion dependent mechanism to translocate toxic effector proteins directly into the eukaryotic cell. READ MORE

  2. 2. Cell signaling by Rho and Miro GTPases : Studies of Rho GTPases in Cytoskeletal Reorganizations and of Miro GTPases in Mitochondrial Dynamics

    Author : Åsa Fransson; Pontus Aspenström; Harry Mellor; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ras superfamily; Rho GTPases; cytoskeleton; Miro GTPases; mitochondrial dynamics; Cell and molecular biology; Cell- och molekylärbiologi;

    Abstract : The Ras superfamily of GTPases embraces six major branches of proteins: the Ras, Rab, Ran, Arf, Rho and Miro subfamilies. The majority of GTPases function as binary switches that cycle between active GTP-bound and inactive GDP-bound states. This thesis will focus primarily on the biological functions of the Rho and Miro proteins. READ MORE