Search for dissertations about: "Rat brain tumor"

Showing result 16 - 20 of 33 swedish dissertations containing the words Rat brain tumor.

  2. 16. Multivariate analyses of proteomic and metabolomic patterns in brain tumors

    Author : Carl Wibom; A Tommy Bergenheim; Henrik Antti; Mikael Johansson; Janne Lehtiö; Umeå universitet; []
    Keywords : glioblastoma; meningioma; proteomics; metabolomics; multivariate analyses; onkologi; Oncology;

    Abstract : Glioblastoma multiforme (GBM) is the most common primary brain tumor. Given the current standard of care, the prognosis for patients diagnosed with this disease is still poor. There consequently exists a need to improve current treatments, as well as to develop new ones. READ MORE

  4. 17. Novel extrahepatic P450 enzymes with emphasis on the tumor specific CYP2W1

    Author : Maria Karlgren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cytochrome P450 is a superfamily of enzymes involved in the metabolism of endogenous and exogenous compounds. The P450 enzymes are expressed at high levels in the liver, but are also found in extrahepatic tissues and in transformed tissues. READ MORE

  5. 18. Molecular studies of the insulin-like growth factor system in the brain : focus on growth, tumorigenesis and trauma

    Author : Ann-Christin Sandberg Nordqvist; Karolinska Institutet; Karolinska Institutet; []
    Keywords : insulin-like growth factors; insulin-like growth factor binding proteins; brain; mRNA; meningioma; glioma; traumatic brain injury; in situ hybridization; Northern blothybridization;

    Abstract : Insulin-like growth factor (IGF) 1 and -2 are synthesized by most tissues of the body and function as autocrine or paracrine agents in a tissue-specific manner. mRNA for IGF-1 and -2, as well as the IGF-binding proteins, are synthesized locally in various regions of the brain. READ MORE

  6. 19. Characterizing and modulating the effects of ionizing radiation to the juvenile hippocampus

    Author : Malin Blomstrand; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; low-dose radiation; CNS; hippocampus; apoptosis; cytokines; growth factors; microglia; medulloblastoma; hippocampal sparing; tumor bed boost; cognitive risk estimation;

    Abstract : Survival rates after childhood cancer treatment have improved, leading to a growing population of survivors. Radiotherapy is an important tool for curing cancer in the brain. Unfortunately, radiotherapy is associated with late side effects e.g. READ MORE

  7. 20. Molecular studies of multiple endocrine neoplasia type 1 (MEN1)

    Author : Shideh Khodaei-O'Brien; Karolinska Institutet; Karolinska Institutet; []
    Keywords : genetics; MEN1; cancer; tumor suppressor gene; cDNA selection; mutation; menin; ortholog; evolution; conservation; expression; RNA; protein; RT-PCR;

    Abstract : Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant familial cancer syndrome characterized by tumors of the parathyroids, the endocrine pancreas and anterior pituitary. The MEN1 locus has been previously localized to chromosome 11q13 and subsequently a MEN1 minimum region was defined by a combination of linkage and tumor deletion studies. READ MORE