Search for dissertations about: "Rat neocortex"

Showing result 1 - 5 of 10 swedish dissertations containing the words Rat neocortex.

  1. 1. An Attractor Memory Model of Neocortex

    Author : Christopher Johansson; Anders Lansner; Stefano Fusi; KTH; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Attractor Neural Networks; Cerebral Cortex; Neocortex; Brain Like Computing; Hypercolumns; Minicolumns; BCPNN; Parallel Computers; Autoassociative Memory; Computer science; Datalogi;

    Abstract : This thesis presents an abstract model of the mammalian neocortex. The model was constructed by taking a top-down view on the cortex, where it is assumed that cortex to a first approximation works as a system with attractor dynamics. READ MORE

  2. 2. Neurogenesis and gliogenesis after focal brain ischemia. Modulation by enriched environment and exercise

    Author : Mila Komitova; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : astrocyte; hippocampus; neural progenitor cells; neural stem cells; neurogenesis; neurotrophins; rat; regeneration; rehabilitation; stroke;

    Abstract : New neurons are formed from dividing neural stem cells in restricted areas in the adult mammalian brain: the dentate gyrus of the hippocampal formation (DG) and the forebrain subventricular zone (SVZ). New glia also form constitutively and seem to be important for neuronal function. READ MORE

  3. 3. Inhibition in cognition : neurophysiology and connectivity of gabaergic interneurons in the prefrontal cortex

    Author : Josina Anna van Lunteren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Abstract : The prefrontal cortex (PFC) is a cortical region involved in higher-order cognitive functions, it is widely connected to the rest of the neocortex and is involved in tasks that require temporal integration of information. The local PFC circuit contains excitatory pyramidal neurons and inhibitory interneurons, and the interplay between these is essential for computations in the PFC. READ MORE

  4. 4. The role of the serotonergic system and the effects of antidepressants during brain development examined using in vivo PET imaging and in vitro receptor binding

    Author : Stal Saurav Shrestha; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Abstract : Serotonin (5-HT) and the serotonergic system, which includes the serotonin transporter (SERT) and the two G protein-coupled 5-HT1A and 5-HT1B receptors, are implicated in the pathophysiology and treatment of several neuropsychiatric disorders including major depressive disorder (MDD) and anxiety. Two classes of antidepressants—selective serotonin reuptake inhibitors (SSRIs), which block SERT, and tricyclic antidepressants (TCAs), which block several monoamine transporters—alter 5-HT levels and modulate the serotonergic system. READ MORE

  5. 5. Development of positron emission tomography radioligands for the dopaminergic and serotonergic neurotransmission systems

    Author : Camilla Lundkvist; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; PET; Radioligand; Dopamine transporter; Serotonin transporter; 5-HT1A receptor; 5-HT2A receptor;

    Abstract : The dopaminergic and serotonergic neurotransmission systems are of central interest in relation to several neuropsychiatric disorders. The main objectives were to develop new suitable radioligands for positron emission tomography (PET) examinations of the dopamine transporter (DAT) as well as the serotonin 5-HT1A and 5-HT2A-receptors. READ MORE