Search for dissertations about: "Recent Integrations"

Found 4 swedish dissertations containing the words Recent Integrations.

  2. 1. Hepatitis B virus RNA in serum and liver tissue - quantification using digital PCR

    Author : Kasthuri Prakash; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hepatitis B virus; NTCP; HBV DNA; HBV RNA; subviral particles; integrations; droplet digital PCR;

    Abstract : Hepatitis B virus (HBV) infection is a global health issue that is responsible for approximately 900,000 deaths each year, by inducing liver cirrhosis and hepatocellular carcinoma (HCC). A few markers are used to classify HBV infection and monitor treatment efficacy, including HBV DNA, surface antigen (HBsAg) and e antigen (HBeAg) in serum as well as HBV DNA and RNA in liver tissue. READ MORE

  4. 2. Genomic Variation and Evolution of HERV-H and other Endogenous Retroviruses (ERVs)

    Author : Patric Jern; Jonas Blomberg; Michael Tristem; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; Endogenous Retrovirus ERV ; HERV-H; Phylogeny; Evolution; Sequence Variation; Polymorphism; Recent Integrations; Horizontal Transfer; Master Elements; Taxonomy; Mikrobiologi; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar;

    Abstract : An exogenous retrovirus (XRV) that integrates into a germ cell may be inherited as a Mendelian gene; it becomes an endogenous retrovirus (ERV). The human genome consists of up to 8% HERVs. The gammaretroviral (ERV class I) HERV-H, with 926 members, is the largest ERV group. READ MORE

  5. 3. Retroviral long Terminal Repeats; Structure, Detection and Phylogeny

    Author : Farid Benachenhou; Jonas Blomberg; Göran Sperber; Aris Katzourakis; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Retrovirus; long terminal repeats; hidden Markov models; phylogeny; alignment; conserved motif; stem-loop; Clinical virology; Klinisk virologi; Klinisk virologi; Clinical Virology;

    Abstract : Long terminal repeats (LTRs) are non-coding repeats flanking the protein-coding genes of LTR retrotransposons. The variability of LTRs poses a challenge in studying them. Hidden Markov models (HMMs), probabilistic models widely used in pattern recognition, are useful in dealing with this variability. READ MORE

  6. 4. Searching for keys to successful post-merger integration : A longitudinal case-study following a public sector merger

    Author : Siw Lundqvist; Christer Carlsson; Leif Marcusson; Rune Gustafsson; Linnéuniversitetet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; post-merger integration; Information Systems; Informatik;

    Abstract : Unsuccessful mergers are unfortunately the rule rather than the exception. Therefore it is necessary to gain an enhanced understanding of mergers and post-merger integrations (PMI) as well as learning more about how mergers and PMIs of information systems (IS) and people can be facilitated. READ MORE