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Showing result 1 - 5 of 17 swedish dissertations matching the above criteria.
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1. Protein tyrosine kinases in insulin producing cells : Expression and putative importance for beta-cell function
Abstract : Protein tyrosine kinases are of importance for cell replication and differentiation in manysystems. The mechanisms controlling the replication and differentiation of insulin producingcells are unknown. READ MORE
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2. Protein Tyrosine Phosphatases as Regulators of Receptor Ryrosine Kinases
Abstract : Tyrosine phosphorylation is a crucial mechanism in cellular signaling and regulates proliferation, differentiation, migration and adhesion. The phosphorylation reaction is reversible and is governed by two families of enzymes: protein tyrosine kinases and protein tyrosine phosphatases (PTPs). READ MORE
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3. Protein tyrosine kinases and the regulation of signalling and adhesion in drosophila melanogaster
Abstract : In order to build a multi-cellular organism and to regulate cellular functions, cells need to communicate with each other, as well as tightly regulate their behaviour in response to environmental changes. For these purposes all eukaryotic cells express a large number of membrane spanning receptors that either themselves contain catalytic activity or via cytoplasmic effector enzymes, function to transmit “signals” from the cell exterior to induce appropriate responses within the cell. READ MORE
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4. T-Cell Protein Tyrosine Phosphatase, a Regulator of the PDGF Signaling Pathway
Abstract : Platelet-derived growth factor (PDGF) is a potent stimulator of cell growth, survival and motility. PDGF exerts its function by binding to specific tyrosine kinase receptors, initiating receptor auotphosphorylation and initiation of specific signaling pathways that regulates the cellular response. READ MORE
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5. The receptor tyrosine kinase Met and the protein tyrosine phosphatase PTPN2 in breast cancer
Abstract : Breast cancer is the most common form of cancer in women worldwide and the second leading cause of cancer death. It is a heterogeneous disease and is subdivided into different subtypes, all with different treatment responses and survival outcomes. READ MORE