Search for dissertations about: "Regenerative medicine"

Showing result 1 - 5 of 106 swedish dissertations containing the words Regenerative medicine.

2. 1. Challenges in Islet Transplantation and Strategies to Improve Beta-Cell Function

   Author : Hanna Liljebäck; Per-Ola Carlsson; James Shaw; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Islet transplantation; Type 1 diabetes; Mesenchymal stem cells; Medical Cell Biology; Medicinsk cellbiologi;

   Abstract : The incidence of type 1 diabetes is increasing worldwide and therapies of islet transplantation and potential cell-based therapies are rapidly evolving. Choosing the optimal site for such therapies is crucial for safety and for obtaining the best possible outcome. READ MORE

4. 2. Studies on glycosphingolipids in regenerative medicine

   Author : Angela Barone; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glycosphingolipids; human embryonic stem cells; Cell surface markers; porcine heart valves; xenotransplantation; regenerative medicinr;

   Abstract : Regenerative medicine, including stem cell based therapies and xenotransplantation, is a new and developing field that aims to restore normal function in end stage cell/organ failure. However, in therapeutic settings involving transfer of cells with a different genetic background, these cells will expose the recipient to non-self cell surface antigenic determinants that may evoke an immune response and subsequent graft damage. READ MORE

5. 3. Expression of Tissue Antigens in Human Pluripotent Stem Cells and Alterations During Differentiation : Potential application in regenerative medicine for treatment of terminal cell and organ failure

   Author : Karin Säljö; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pluripotent stem cells; Differentiation; Histo-blood group antigens; HLA; Tissue antigens; Sialyl-lactotetra; Cell surface antigens; Transplantation; Regenerative medicine;

   Abstract : The major limiting factor in the treatment of patients with end-stage organ failure is the insufficient number of human organs available for transplantation. An unlimited access to human cells, tissues and organs would also open up possibilities to treat several chronic diseases, such as diabetes, neurological and cardiovascular diseases, affecting millions of patients worldwide. READ MORE

6. 4. The impact of signaling factors on intervertebral disc degeneration and regeneration - studies on disc and mesenchymal stem cells from chronic low back pain patients

   Author : Daphne Hingert; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Regenerative medicine; Translational medicine;

   Abstract : INTRODUCTION: Chronic low back pain (LBP) is associated with degeneration of the intervertebral discs (IVDs). Increased expressions of pro-inflammatory cytokines such as interleukin-1β (IL-1β) and matrix metalloproteinases (MMPs) in degenerated IVDs lead to loss of proteoglycan and extracellular matrix (ECM) which affect the viability of the disc cells (DCs). READ MORE

7. 5. Collagen Hydrogels for Regenerative Medicine

   Author : Justina Pupkaite; Peter Påhlsson; Erik Suuronen; May Griffith; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : The need for regenerative therapies to repair damaged or deteriorated organs and tissues, such as heart, skin, and cornea, is rising due to donor shortage and aging of the world’s population. Many proposed regenerative therapeutic approaches include a combination of cells, bioactive compounds, and hydrogels. READ MORE