Search for dissertations about: "Regenerative medicine"
Showing result 6 - 10 of 106 swedish dissertations containing the words Regenerative medicine.
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6. Human embryonic stem cells for bone engineering applications
Abstract : The human skeleton represents the supporting structure of the organism and accounts for about 20 percent of the total body mass. Despite its intrinsic capacity to regenerate and self-repair, this ability is limited and repair therapies are needed in a large number of clinical cases. READ MORE
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7. Molecular and structural patterns of guided bone regeneration (GBR). Experimental studies on the role of GBR membrane and bone substitute materials
Abstract : The mechanisms of guided bone regeneration (GBR) and bone healing with calcium phosphate (CaP) bone substitutes are not fully understood. The major aim of this thesis was to determine the relationship between the bone formation in bone defects and the cellular distribution and activities in association with CaP materials and/or with GBR membrane. READ MORE
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8. The osteogenic potential of human mesenchymal stem cells: Novel markers and key factors for differentiation
Abstract : Mesenchymal stem cells are multipotent stem cells with ability to differentiate into cells of the connective tissue lineage, such as adipocytes, osteoblasts and chondrocytes, both in vitro and in vivo. The main objective of the present thesis was to study different aspects of the osteogenic potential of MSCs. READ MORE
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9. Human Bone Marrow Microenvironment in Health and Disease
Abstract : Hematopoietic stem cells (HSCs) are safeguarded from various threats such as stress, injury, or radiationwithin specialized microenvironments or niches within the bone marrow. In this thesis, we investigatedvarious facets of the bone marrow (BM) microenvironment and its critical role in hematopoiesis andrelated disorders. READ MORE
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10. Aging Hematopoiesis: Functional Insights and Prospects for Rejuvenation
Abstract : Aging exerts profound effects on the hematopoietic system, leading to a loss of homeostatic control and reduced regenerative capacity. Clinical consequences of these changes include anemia, compromised immune function and an increased prevalence of myeloid disorders among the elderlies. READ MORE