Search for dissertations about: "Regulatory Sequences"
Showing result 6 - 10 of 109 swedish dissertations containing the words Regulatory Sequences.
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6. Regulation of protein degradation by virus derived repeated amino acid sequences
Abstract : The ubiquitin-proteasome pathway plays a central role in the controlled degradation of short-lived and regulatory proteins important m a variety of cellular processes, including antigen presentation and combating viral infections. The presentation of antigenic peptides derived from ubiquitin-proteasome dependent degradation of vital proteins to MHC class I restricted cytotoxic T cells is a central component of antiviral responses. READ MORE
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7. Gene regulatory evolution in flycatchers: statistical approaches for the analysis of allele-specific expression
Abstract : Understanding the molecular mechanisms underlying evolutionary changes in gene expression is a major research topic in biology. While a powerful approach to study this is the analysis of allele-specific expression (ASE), most of previously published methods can only be applied to lab organisms. READ MORE
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8. A genomic approach to smooth muscle differentiation and diversity
Abstract : Smooth muscle cells (SMCs) are a broad class of contractile cells that are found in a number of organs systems, including the vasculature, the urogenital system, the bronchi and the gastrointestinal tract. The two main functions exerted by SMCs are to provide contractile force and to synthesize structural components of the extracellular matrix. READ MORE
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9. Studies on the Molecular Biology of the Mouse Pneumotropic Polyomavirus
Abstract : The Murine Pneumotropic Virus (MPtV), in contrast to the other MurinePolyomavirus (MPyV), appears to be non-tumourigenic in its natural host. Instead, MPtV causes acute pneumonia and can serve as a model in studies of polyomavirus-induced disease. In initial experiments, MPtV large T-antigen (LT) was expressed in a heterologous system. READ MORE
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10. Advances in studying the role of genetic divergence and recombination in adaptation in non-model species
Abstract : Understanding the role of genetic divergence and recombination in adaptation is crucial to understanding the evolutionary potential of species since they can directly affect the levels of genetic variation present within populations or species. Genetic variation in the functional parts of the genome such as exons or regulatory regions is the raw material for evolution, because natural selection can only operate on phenotypic variation already present in the population. READ MORE