Search for dissertations about: "Regulatory State"

Showing result 11 - 15 of 218 swedish dissertations containing the words Regulatory State.

  1. 11. Regulatory mechanisms controlling T cell activity

    Author : Anette Sundstedt; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; T cell superantigen anergy interleukin-2 transcription factor cytotoxicity; serology; Immunology; Immunologi; serologi;

    Abstract : This thesis is based on work studying the immunoregulatory mechanisms that govern the balance between activation and inactivation of T lymphocytes. Most of the work has been carried out in an experimental system using a T cell receptor (TCR-Vb3) transgenic mouse strain to obtain a homogenous T-cell population and utilizing the properties of bacterial superantigens to induce T cell responses and unresponsiveness in vivo. READ MORE

  2. 12. Studies on the function of CD4CD25 regulatory T cells: An in vitro approach

    Author : Lukas Cederbom; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; CD152; Costimulation; Dendritic cells; Regulatory T cells; CD4 CD25 ; serology; transplantation; Immunologi; serologi;

    Abstract : Immunological self-tolerance is a state of the whole organism where deleterious responses are either avoided or regulated. Breaking of immunological tolerance will lead to autoimmune disease or chronic inflammatory conditions. READ MORE

  3. 13. Investigating novel roles of topoisomerase regulatory interactions in transcription

    Author : Vladislav Kuzin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Drugs targeting DNA Topoisomerases (TOPs, TOP1 and TOP2) are mainstays of anti-cancer therapy. While they have proven effective, the toxicity of current TOP drugs caused by DNA damage-induced apoptosis of non-cancer cells, limits their use in the clinic. READ MORE

  4. 14. Regulatory Functions of Protein Phosphorylation in Plant Photosynthetic Membranes

    Author : Rikard Fristedt; Alexander Vener; Thomas Pfannschmidt; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Oxygenic photosynthesis is the process in plants, algae and cyanobacteria which converts light energy from the sun into carbohydrates and at the same time produces oxygen from water. Both carbohydrates and oxygen are essential to sustain life on earth. READ MORE

  5. 15. The EU Services Directive – Law or Simply Policy?

    Author : Maria Wiberg; Jane Reichel; Antonina Bakardjieva Engelbrekt; Ulla Neergaard; Uppsala universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Services Directive; free movement of services; internal market; regulatory autonomy; new governance;

    Abstract : The balance between the regulatory autonomy of the Member State of the European Union and the requirements of harmonisation as set out in the EU Services Directive (2006/123/EC) is the subject of this work. The overall effects of the free movement of services on national regulatory autonomy as prescribed by the Services Directive is to a great degree dependent upon whether this directive is perceived of as a traditional directive or instead, as a governance instrument to control and steer the actions of the Member States. READ MORE