Search for dissertations about: "Relative biological effectiveness in proton therapy"

Showing result 1 - 5 of 8 swedish dissertations containing the words Relative biological effectiveness in proton therapy.

  2. 1. Relative biological effectiveness in proton therapy: accounting for variability and uncertainties

    Author : Jakob Ödén; Iuliana Toma-Dasu; Kjell Eriksson; Radhe Mohan; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proton therapy; relative biological effectiveness; linear energy transfer; proton track-end optimisation; radiation-induced toxicity; Medical Radiation Physics; medicinsk strålningsfysik;

    Abstract : Radiation therapy is widely used for treatments of malignant diseases. The search for the optimal radiation treatment approach for a specific case is a complex task, ultimately seeking to maximise the tumour control probability (TCP) while minimising the normal tissue complication probability (NTCP). READ MORE

  4. 2. Interlaced proton grid therapy: development of an innovative radiation treatment technique

    Author : Thomas Henry; Irena Gudowska; Tony Lomax; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proton therapy; grid therapy; spatially fractionated therapy; interlacing; Medical Radiation Physics; medicinsk strålningsfysik;

    Abstract : Spatially fractionated radiotherapy, also known as grid therapy (GRID), has been used for more than a century to try to treat several kinds of lesions. Yet, the grid technique remains a relatively unknown and uncommon treatment modality nowadays. READ MORE

  5. 3. Techniques for the increased utilization of dose response variability in proton therapy

    Author : Erik Almhagen; Anders Ahnesjö; Alexandru Dasu; Nina Tilly; Oliver Jäkel; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; RBE; Radiobiology; Proton Therapy; Dose Painting; Head and Neck Cancer; Medicinsk vetenskap; Medical Science;

    Abstract : Particle therapy is a form of radiation therapy in which protons and heavier ions are used, as opposed to photons in conventional radiation therapy. The biological effectiveness of particles compared to photons is often quantified as relative biological effectiveness (RBE). READ MORE

  6. 4. Radiobiological investigations of proton and light ion therapy

    Author : Nina Tilly; Michael Scholz; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiobiology; Monte Carlo method; Radiotherapy; high-energy instrumentation; Protons; Light ions; RBE; LET; Radiobiological models; Radiobiologi; medicinsk strålningsfysik; Medical Radiation Physics;

    Abstract : During the last decade, the interest in proton and light ion beam therapy has increased considerably and several new centres are planned around the world. These particles have a large advantage due to their sharp physical dose distributions as compared to conventional radiotherapy beams. READ MORE

  7. 5. Monte Carlo particle transport codes for ion beam therapy treatment planning : Validation, development and applications

    Author : Till Tobias Böhlen; Irena Gudowska; Oliver Jäkel; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Monte Carlo; ion beam therapy; treatment planning; cancer therapy; microdosimetry; Medical Radiation Physics; medicinsk strålningsfysik;

    Abstract : External radiotherapy with proton and ion beams needs accurate tools for the dosimetric characterization of treatment fields. Monte Carlo (MC) particle transport codes, such as FLUKA and GEANT4, can be a valuable method to increase accuracy of dose calculations and to support various aspects of ion beam therapy (IBT), such as treatment planning and monitoring. READ MORE