Search for dissertations about: "Release mechanism"
Showing result 1 - 5 of 519 swedish dissertations containing the words Release mechanism.
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1. Poly(Lactide-co-Glycolide) in Controlled-Release Pharmaceuticals - Release Mechanisms
Abstract : Controlled-release formulations reduce the frequency of injections and better maintain plasma concentrations within the therapeutic window. Poly(D,L-lactide-co-glycolide) (PLG) is currently the most frequently used biodegradable polymer for this application. READ MORE
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2. Characterization of the Mechanisms of Drug Release from Polymer-Coated Formulations using Experiments and Modelling
Abstract : The main objectives of the work presented in this thesis were to develop new experimental methods to improve the understanding of the release mechanism from a coated formulation and to develop new mechanistic models to describe the release process for pellets coated with a semi-permeable film. Another aim was to characterize the release mechanism from a formulation coated with films made of a blend of a water-insoluble polymer, ethyl cellulose (EC), and a water-soluble polymer, hydroxypropyl cellulose (HPC). READ MORE
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3. Modelling of Drug Release from Reservoir and Matrix Formulations - Multiple Unit Dosage Forms and Swelling and Dissolving Matrix Systems
Abstract : In this work, mathematical models have been developed describing drug release from film-coated reservoir systems as well as drug release and polymer dissolution from swelling and dissolving polymer tablets. The model derivation of both systems is based on a mechanistic approach. The model describing drug release from reservoir systems, i.e. READ MORE
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4. Viperin vs. tick-borne encephalitis virus : mechanism of a potent antiviral protein
Abstract : Tick-borne encephalitis virus (TBEV) is a very important virus medically, causing mild or severe encephalitis often with long-lasting sequelae. Treatment of tick-borne encephalitis is limited to supportive care, and antiviral drugs are much needed.The type-I interferon (IFN) system is the first line of host defense against many viruses. READ MORE
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5. Formation and Decomposition of Platinum–Thallium Bond, Kinetics and Mechanism. Structural Characterization of Some Metal Cyanides in the Solid State
Abstract : The kinetic and mechanistic features of a new series ofplatinum-thallium cyano compounds containing a direct andunsupported by ligands metal-metal bond have been studied insolution, using standard mixandmeasurespectrophotometric technique and stoppedflow method.These reactions are interpreted as oxidative addition of the cspecies to the square planar Pt(CN)42-complex. READ MORE