Search for dissertations about: "Repression"

Showing result 21 - 25 of 258 swedish dissertations containing the word Repression.

  2. 21. Deciphering mechanisms of transcriptional activation and repression in B lymphocytes

    Author : Stephen Malin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : During the course of evolution, our immune system has developed, to defend us against infections, a diverse number of specialized cell types. Immunoglobulin producing B lymphocytes are produced by the differentiation of hematopoietic stem cells (HSC) into gradually more lineage-restricted progenitors. READ MORE

  4. 22. Functional studies in yeast of cyclin C and the RNA polymerase II Mediator complex

    Author : Darius Balciunas; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Cyclin C; RNA polymerase II; Mediator; glucose repression; RAS cAMP pathway; Saccharomyces cerevisiae; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

    Abstract : Cyclin C belongs to a group of cyclins that are not cell cycle-regulated. It was first cloned from Drosophila and rat, but its role was not understood until the yeast cyclin C homologue Srb 11 was identified in several genetic screens for transcriptional repressors and subsequently was shown to be associated with the RNA polymerase II Mediator complex. READ MORE

  5. 23. Global Regulation of Snf1 in Saccharomyces cerevisiae: A case study of experimental systems biology

    Author : Jie Zhang; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; AMP-activated protein kinase AMPK ; glucose derepression; energy homeostasis; target of rapamycin complex 1 TORC1 ; catabolite repression; Snf1;

    Abstract : Cells commonly face environmental changes and have evolved various regulatory mechanisms to adjust their metabolism accordingly. One such key regulator in S. cerevisiae is the Snf1 kinase, which belongs to the conserved AMP-activated protein kinase (AMPK) family in all eukaryotes. READ MORE

  6. 24. Characterisation of the Clp Proteins in Arabidopsis thaliana

    Author : Bo Zheng; Adrian K. Clarke; Vaughan Hurry; Cecilia Sundby-Emanuelsson; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Plant physiology; Arabidopsis; molecular chaperone; protein degradation; protease; Clp Hsp100; ClpP; stress response; antisense repression; chloroplast development; Växtfysiologi; Plant physiology; Växtfysiologi; molekylärbiologi; Molecular Biology;

    Abstract : Unlike in the greenhouse, plants need to cope with many environmental stresses under natural conditions. Among these conditions are drought, waterlogging, excessive or too little light, high or low temperatures, UV irradiation, high soil salinity, and nutrient deficiency. READ MORE

  7. 25. Three Subfamilies of KRAB Zinc Finger Proteins : A Structural, Functional and Evolutionary Analysis

    Author : Charlotta Mark; Lars Hellman; Fredrik Öberg; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biology; Krüppel zinc finger; KRAB; TIF1β; transcriptional repression; Biologi; Biology; Biologi; Molecular Immunology; molekylär immunologi;

    Abstract : Krüppel-related zinc finger proteins constitute the largest single class of transcription factors within the human genome. Members of this protein family have the ability to either activate or repress transcription depending on the presence of specific activator or repressor domains within the protein. READ MORE