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Showing result 1 - 5 of 39 swedish dissertations matching the above criteria.

2. 1. Reproducible Data Analysis in Drug Discovery with Scientific Workflows and the Semantic Web

   Author : Samuel Lampa; Ola Spjuth; Roland Grafström; Konrad Hinsen; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Reproducibility; Scientific Workflow Management Systems; Workflows; Pipelines; Flow-based programming; Predictive modelling; Semantic Web; Linked Data; Semantic MediaWiki; MediaWiki; RDF; SPARQL; Golang; Reproducerbarhet; Arbetsflödeshanteringssystem; Flödesbaserad programmering; Prediktiv modellering; Semantiska webben; Länkade data; Go; Bioinformatics; Bioinformatik; Pharmacology; Farmakologi;

   Abstract : The pharmaceutical industry is facing a research and development productivity crisis. At the same time we have access to more biological data than ever from recent advancements in high-throughput experimental methods. READ MORE

4. 2. Studies on bikeability in a metropolitan area using the active commuting route environment scale (ACRES)

   Author : Lina Wahlgren; Peter Schantz; Henrik Gustafsson; Pekka Oja; Örebro universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; active transport; bicycle commuting; bikeability; multiple linear regression analysis; perception; reliability; route environment; validity; Sports; Idrott; Sports Science; Idrottsvetenskap; Samhällsvetenskap Humaniora;

   Abstract : Background: The Active Commuting Route Environment Scale (ACRES) was developed to study active commuters’ perceptions of their route environments. The overall aims were to assess the measuring properties of the ACRES and study active bicycle commuters’ perceptions of their commuting route environments. READ MORE

5. 3. Radiological measurements in total hip arthroplasty

   Author : Bariq Al-Amiry; Arkan Sayed-Noor; Torkel Brismar; Seppo Koskinen; Mats Geijer; Umeå universitet; []
   Keywords : Total hip arthroplasty; leg length discrepancy; femoral offset; WOMAC; quality of life; radiographicmeasurements; Kellgren-Lawrence; duration; acetabular cup; inclination; anteversion; BMI;

   Abstract : Every year, about 1 million patients worldwide and 20000 patients in Sweden undergo total hip arthroplasty (THA). This type of operation is considered a successful, safe and cost-effective procedure to regain mobility and restore hip joint function in patients suffering from severe hip joint disease or trauma. READ MORE

6. 4. Leg length discrepancy and femoral offset after total hip arthroplasty : clinical and radiological studies

   Author : Sarwar Mahmood; Arkan Sayed-Noor; Sead Crnalic; Gösta Ullmark; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Total hip arthroplasty; leg flength discrepancy; femoral offset; WOMAC; quality of life; complication; radiographic measurements; acetabular cup; inclination; anteversion; Orthopaedics; ortopedi;

   Abstract : Every year, about 1 million patients worldwide and 16000 patients in Sweden undergo total hip arthroplasty (THA). This surgical intervention is considered a successful, safe and cost-effective procedure to regain pain-free mobility and restore hip joint function in patients suffering from severe hip joint disease or trauma. READ MORE

7. 5. Membrane protein proteomics - Novel method for membrane protein identification and quantification

   Author : Maria Bentz; Institutionen för immunteknologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biokemisk teknik; mebran; steroider; Lipider; membranes; steroids; Lipids; enzymologi; Proteiner; Membrane proteins; Proteomics; Proteinase K; N-terminal labelling; Relative Quantitation; Database search; Cancer; Cytology; oncology; cancerology; Cytologi; onkologi; cancer; enzymology; Proteins; Biochemical technology;

   Abstract : Membrane proteins are fairly refractory to digestion especially by trypsin. Less specific proteases like elastase and pepsin are much more effective. However database searching using non-tryptic peptides is much less effective due to the lack of charge localisation at the N- and C-termini and the absence of sequence specificity. READ MORE