Search for dissertations about: "Retinal transplants"

Showing result 1 - 5 of 6 swedish dissertations containing the words Retinal transplants.

2. 1. Retinal Transplants: Growth Differentiation Integration Organization and Survival

   Author : Rajesh Kumar Sharma; Lund Oftalmologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; retinal degeneration; Retinal transplants; retinal development; treatment; connections; proliferation; survival; Ophtalmology; Oftalmologi;

   Abstract : The goal of the study was to get a better understanding of factors controlling the growth, differen-tia-tion, integration, organization and survival of retinal transplants, with the long-term view of eventually developing retinal transplantation into a clinically useful procedure for treating degenerative retinal disorders such as retinitis pigmentosa. Embryonic day 15 rabbit retinas were transplanted into adult rabbit eyes and were allowed to survive for various times. READ MORE

4. 2. Photoreceptors in experimental retinal cell transplants

   Author : Bengt Juliusson; Lund Oftalmologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ophtalmology; immunohistochemistry; mice; rabbits; rats; interphotoreceptor matrix; retinal pigment epithelium; photoreceptors; Retina; transplantation; Oftalmologi;

   Abstract : The main objective of this thesis was to investigate the fate of photoreceptor cells when using different strategies for retinal cell transplantation. Comparing transplantation of fragments of embryonic retina with cell suspensions of the same tissue we found that transplantation of fragments of embryonic retina result in mature transplants with a higher degree of cellular organization than transplantation of cell suspensions of embryonic retina. READ MORE

5. 3. Interactions between neural retina, retinal epithelium and choroid

   Author : Lena Ivert; Karolinska Institutet; Karolinska Institutet; []
   Keywords : RPE; neural retina; basal lamina; Bruch s membrane; choroid; subretinal space; bleb detachment; ICG; FAG; SLO; choroidal blood flow.;

   Abstract : The retinal pigment epithelium (RPE) is a non-replicating monolayer that plays a key role nursing the photoreceptors of the neural retina, regulating fluid movement within the subretinal space, maintaining a basal laminar layer of Bruch s membrane, and influencing the choriocapillaris. This project investigates how surgical manipulation of the retinal epithelial layer influences the neural retina, the choroid and the epithelial layer itself. READ MORE

6. 4. Experimental Neuroretinal Transplantation

   Author : Fredrik Ghosh; Lund Oftalmologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transplant; Retinal degeneration; Retina; Rabbit; Neural development; Immunohistochemistry; MHC; Ultrastructure; Vitrectomy; Ophtalmology; Oftalmologi;

   Abstract : Embryonic full-thickness rabbit neuroretinal sheets were transplanted to the subretinal space of adult hosts. This was accomplished by using a new transplantation technique involving vitrectomy and retinotomy. The grafts were followed from 10 to 306 days after surgery, and were then examined by different histological techniques. READ MORE

7. 5. Experimental transplantation of retinal and iris pigment epithelial cells into the subretinal space

   Author : Sven Crafoord; Jan Ulrik Prause; Linköpings universitet; []
   Keywords : MEDICINE; MEDICIN;

   Abstract : A dysfunction of the retinal pigment epithelium (RPE) is the main cause for the development of age-related macular degeneration (ARMD) and visual loss in elderly people. For about 10 years experimental and clinical attempts to transplant RPE cells have been performed. READ MORE