Search for dissertations about: "Retinitis pigmentosa"

Showing result 16 - 20 of 21 swedish dissertations containing the words Retinitis pigmentosa.

  2. 16. Improving animal models to understand gene regulation in human diseases

    Author : Abdul Kadir Mukarram; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The role of animal models in understanding biological processes and their dysregulations in humans is imperative and established in the research community. While extensive resources and knowledge on the genetic information of popular organisms such as human and mouse exist, such resources are lacking for other strong popular organisms like zebrafish and dogs. READ MORE

  4. 17. Electrophysiology and optical coherence tomography in acquired and hereditary retinal disorders

    Author : Patrik Schatz; Lund Oftalmologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Retinal degeneration; multifocal ERG; Oftalmologi; Ophtalmology; OCT;

    Abstract : In this thesis, retinal function in general, as well as central retinal function and structure are described in selected forms of acquired and hereditary retinal disorders, in order to improve our understanding of underlying pathogenic mechanisms. This comparison has been made possible during the last years, through the relatively recent development of multifocal ERG (mfERG) and optical coherence tomography (OCT) for the analysis of central retinal function and structure, respectively. READ MORE

  5. 18. Studies into The Mechanisms of Neurodegeneration and Neuroprotection in Rd1 Mouse Retina

    Author : Seifollah Azadi; Lund Oftalmologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; signaling pathway ; Ophtalmology; neurotrophic factors ; Oftalmologi; retina degeneration ;

    Abstract : Retinitis Pigmentosa (RP) is a group of uncured retinal diseases with the world wide incidence of about 1/3500. In spite of the huge efforts in past years, the mechanisms underlying this type of hereditary blindness has not been elucidated and nor any effective treatment available. READ MORE

  6. 19. Photoreceptor degeneration, second order neuron remodeling and glia reactivity in an in vivo and in vitro model of retinal neurodegeneration

    Author : Tanzina Mollick; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicin; Biomedicine;

    Abstract : Photoreceptors have the ability to last during the entire lifespan of an individual. Being the first line of neurons in the visual transduction pathway, their health and maintenance is eminent for proper retinal function. However, photoreceptors are susceptible to neurodegenerative retinal dystrophies. READ MORE

  7. 20. Retinal function in deaf-blind syndromes

    Author : Eva Malm; Lund Oftalmologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; general anesthesia.; molecular genetics; hearing impairment; full-field electroretinography; Retinal degeneration;

    Abstract : A variety of disorders can cause retinal degeneration and hearing impairment, and it is of great value to have an early diagnosis since there is a large variation in phenotype and prognosis both within and between the different disorders. The general aim of this thesis was to characterize the retinal function, to describe the phenotype, and – where appropriate – to relate the phenotype to genotype in patients with combined visual and hearing impairment. READ MORE