Search for dissertations about: "Retinoic acid"

Showing result 16 - 20 of 129 swedish dissertations containing the words Retinoic acid.

  2. 16. Regulation and function of the Mad/Max/Myc network during neuronal and hematopoietic differentiation

    Author : Anne Hultquist; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Myc; Mad1; neuroblastoma; hematopoiesis; phorbol ester; retinoic acid; interferon-g; TGF-b; differentiation.; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Abstract : The Mad/Max/Myc transcription factor network takes part in the control of vital cellular functions such as growth, proliferation, differentiation and apoptosis. Dimerization with the protein Max is necessary for the Myc-family of oncoproteins and their antagonists, the Mad-family proteins, to regulate target genes and carry out their intended functions. READ MORE

  4. 17. Phenotype and function of intestinal CD103+ dendritic cells

    Author : Elin Jaensson Gyllenbäck; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CD103; dendritic cell; CX3CR1; small intestine; MLN; CCR9; Vitamin A; retinoic acid;

    Abstract : Mucosal tissues such as the intestine present an enormous surface area to the outside environment and are continually exposed to foreign antigens in food and microflora. Thus, the intestinal mucosa must must remain tolerant to these innocuous antigens while at same time be able to mount effective immune responses to pathogens. READ MORE

  5. 18. Signaling mechanisms underlying neural stem cell differentiation. Implications of BMPs, retinoids, and MAP kinases

    Author : Roland Faigle; Göteborgs universitet; []
    Keywords : neural stem cells; differentiation; BMP; ASK1; p38 MAP kinase; CNTF; retinoic acid;

    Abstract : Introduction: Neural stem cells are proliferating cells, derived from the nervous system with the ability to give rise to neurons, astrocytes, and oligodendrocytes. The molecular events and signaling pathways regulating neural stem cell differentiation are largely unknown. READ MORE

  6. 19. New aspects on retinoic acid induced HL-60 granulocytic differentiation

    Author : Agnè Kulytè; Tor Olofsson; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The underlying mechanisms of myeloid cell differentiation are still not entirely elucidated. It is therefore an urgent task to extent the basis for a comprehensive model of granulocytes differentiation. A primary goal for studies has been the identification of differentiation markers. READ MORE

  7. 20. Phenotypic and functional analysis of the mesenchymal stromal cell compartment in the thymus

    Author : Katarzyna Sitnik; Slemhinnans immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; thymus; mesenchymal cells; retinoic acid; thymic epithelial cells;

    Abstract : T cells are key cellular components of the adaptive immune system that play a critical role in our defense against pathogens and cancer but also contribute to pathology in the setting of chronic inflammation and autoimmunity. The thymus constitutes the body's major T cell production site, where bone marrow-derived progenitors migrate in a co-ordinated fashion through anatomically distinct cortical and medullary regions that are composed of epithelial and mesenchymal stromal elements. READ MORE