Search for dissertations about: "Reumatologi och molekylär skelettbiologi"

Showing result 16 - 20 of 37 swedish dissertations containing the words Reumatologi och molekylär skelettbiologi.

  2. 16. Systemic sclerosis. Novel molecular and epidemiological features of disease

    Author : Kristofer Andréasson; Reumatologi och molekylär skelettbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic sclerosis; fibrosis; COMP; calprotectin; biomarker; gastrointestinal;

    Abstract : Systemic sclerosis (SSc) is a systemic rheumatic disease with significant mortality and morbidity. Different estimations of disease prevalence and incidence have been presented from various parts of the world. READ MORE

  4. 17. Health economics and its measures in rheumatoid arthritis

    Author : Johan Karlsson; Reumatologi och molekylär skelettbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cost-utility analysis; Cost-of-illness; Quality of life; EuroQol 5-Dimensions; Antirheumatic agents; TNF inhibition; Outcome assessment; Disease activity; Disability; Health economics; Rheumatoid arthritis;

    Abstract : Objectives: To study: (I) the impact on cost-utility analyses of applying different national EuroQol 5-Dimensions (EQ-5D) preference sets; (II and III) whether, in methotrexate-refractory, early rheumatoid arthritis (RA), the addition of infliximab results in superior health-related quality of life (HRQoL) and may be considered cost-effective, as compared to adding sulfasalazine and hydroxychloroquine; (IV) how costs relate to disability (measured by the health-assessment questionnaire, HAQ), disease activity (28-joint disease activity score, DAS28) and HRQoL (EQ-5D) in RA. Methods: In the observational SSATG register, one-year quality-adjusted life-year (QALY) accumulation of two interventions was compared according to the UK, US, or Danish EQ-5D preference sets. READ MORE

  5. 18. Studies on chondroadherin-an extracellular matrix leucine-rich repeat protein

    Author : Christina Wenglén; Reumatologi och molekylär skelettbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk biologi; Clinical biology; COMP; SLRP; ECM; collagen; cartilage; chondroadherin;

    Abstract : This thesis describes chondroadherin, one of the leucine-rich repeat proteins in the extracellular matrix (ECM) of cartilage. Chondroadherin defines a subgroup of its own by not having an N-terminal extension, having a different cysteine pattern and by being devoid of carbohydrate substitutions. READ MORE

  6. 19. Monitoring Arthritis - Biochemical, Metodological and Clinical Aspects

    Author : Maria Andersson; Reumatologi och molekylär skelettbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Monitoring; COMP; CRP; Biomarkers; Rheumatoid Arthritis; Arthritis; Osteoarthritis; Clinical; Diurnal variation;

    Abstract : Arthritides are musculoskeletal diseases, which predominantly affect the joints e.g. osteoarthritis (OA) and rheumatoid arthritis (RA). Modern treatment strategies include early detection and careful monitoring of the disease course. READ MORE

  7. 20. Juvenile idiopathic arthritis - from macrophage to mortality

    Author : Elisabet Berthold; Reumatologi och molekylär skelettbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Juvenile idiopathic arthritis; Epidemiology; outcome evaluation; Monocytes; Inflammation; Depression and Anxiety;

    Abstract : Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in children. Studies of the immunopathogenesis in JIA has mainly focused on the adaptive immune system, while less is known of the role of the monocytes. READ MORE