Search for dissertations about: "Ribosomer"
Showing result 1 - 5 of 11 swedish dissertations containing the word Ribosomer.
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1. Structural and functional studies of the ribosomes : a closer look at expansion segments and translational dynamics in eukaryotes
Abstract : The ribosome is the basic machinery for protein synthesis in all living cells. In the last decade, there has been an explosion of structural information on the ribosome. The eukaryotic ribosome is larger than the prokaryotic counterpart and contains several extra features, even though they have similar core structures. READ MORE
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2. Choice of tRNA on Translating Ribosomes
Abstract : This thesis addresses different aspects of the question about accuracy of protein synthesis: i) the mechanism of tRNA selection during translation ii) study of ribosomal mutations that affect accuracy and iii) the choice of aminoacyl-tRNA isoacceptors on synonymous codons.By measuring the codon reading efficiencies of cognate and near-cognate ternary complexes we demonstrate that in optimal physiological conditions accuracy of substrate selection is much higher than previously reported; that during translation the ribosomal A site is not blocked by unspecific binding of the non-cognate tRNAs which would inhibit the speed of protein synthesis. READ MORE
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3. Ribosomes and subunits from Escherichia coli studied by asymmetrical flow field-flow fractionation
Abstract : In this thesis asymmetrical flow field-flow fractionation (FFF) separations of ribosomes and subunits have been studied. Ribosomal material was prepared from Escherichia coli (E. coli) cells and analyzed by the size separation technique. READ MORE
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4. Systems biology techniques show high prevalence of post-translational regulation in the cyanobacterium Synechocystis PCC 6803
Abstract : Earth's climate has been upset by carbon dioxide (CO2) emissions from human activities and the use of fossil resources. To prevent catastrophic events on the environment and on civilizations, we urgently need to develop alternative solutions that utilize renewable resources. READ MORE
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5. Adaptations and constraints associated with autotrophy in microbial metabolism
Abstract : Carbon dioxide (CO2) emissions from human activities are driving climate change, but the pending crisis could be mitigated by a circular carbon economy where released CO2 is recycled into commodity chemicals. Autotrophic microbes can make a contribution by producing chemicals, such as biofuels, from CO2 and renewable energy. READ MORE