Search for dissertations about: "Richard Bonneau"

Found 2 swedish dissertations containing the words Richard Bonneau.

  2. 1. In silico modelling for refining gene regulatory network inference

    Author : Thomas Hillerton; Erik L. L. Sonnhammer; Richard Bonneau; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Gene regulatory networks; simulation; benchmarking; method development; biokemi med inriktning mot bioinformatik; Biochemistry towards Bioinformatics;

    Abstract : Gene regulation is at the centre of all cellular functions, regulating the cell's healthy and pathological responses. The interconnected system of regulatory interactions is known as the gene regulatory network (GRN), where genes influence each other to maintain strict and robust control. READ MORE

  4. 2. Exploring the Boundaries of Gene Regulatory Network Inference

    Author : Andreas Tjärnberg; Erik Sonnhammer; Richard Bonneau; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; GRN; gene regulatory network; network inference; signal to noise ratio; model selection; variable selection; data properties; reverse engineering; ordinary differential equations; gene networks; linear regression; lasso; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

    Abstract : To understand how the components of a complex system like the biological cell interact and regulate each other, we need to collect data for how the components respond to system perturbations. Such data can then be used to solve the inverse problem of inferring a network that describes how the pieces influence each other. READ MORE