Search for dissertations about: "Richard Buckingham"

Found 5 swedish dissertations containing the words Richard Buckingham.

  1. 1. Versatile Implementations of an Improved Cell-Free System for Protein Biosynthesis : Functional and structural studies of ribosomal protein L11 and class II release factor RF3. Novel biotechnological approach for continuous protein biosynthesis

    Author : Lamine Bouakaz; Måns Ehrenberg; Richard Buckingham; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Protein synthesis; translation termination; ribosome; release factor; cell-free system; missense error; gel filtration; affinity chromatography; Molekylärbiologi; Molecular biology; Molekylärbiologi;

    Abstract : Advances in genetics, proteomics and chromatography techniques have enabled the successfully generation of a cell-free bacterial translation system composed of highly pure and active components. This system provided an ideal platform for better elucidating the mechanism of each individual step of the prokaryotic protein biosynthesis and the function of the translation factors involved in the process. READ MORE

  2. 2. Engendering Spatial Planning : A Gender Perspective on Municipal Climate Change Response

    Author : Christian Dymén; Göran Cars; Richard Langlais; Susan Buckingham; KTH; []
    Keywords : SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Spatial planning; climate change; gender perspective; Planering och beslutsanalys; Planning and Decision Analysis;

    Abstract : While climate change mitigation has been on the agenda of spatial planning practitioners for over two decades, adaptation has only become influential in spatial planning practice in recent years. This trend is evident not only at the municipal levelbut also at the regional and national levels. READ MORE

  3. 3. EF-Tu and RNase E : Essential and Functionally Connected Proteins

    Author : Disa L. Hammarlöf; Diarmaid Hughes; Måns Ehrenberg; Gerhart Wagner; Richard H Buckingham; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; bacterial growth; translation; EF-Tu; RNase E; mRNA; RNA degradation; Molekylär cellbiologi; Molecular Cellbiology; Mikrobiologi; Microbiology;

    Abstract : The rate and accuracy of protein production is the main determinant of bacterial growth. Elongation Factor Tu (EF-Tu) provides the ribosome with aminoacylated tRNAs, and is central for its activity. In Salmonella enterica serovar Typhimurium, EF-Tu is encoded by the genes tufA and tufB. READ MORE

  4. 4. A Few Strokes to the Family Portrait of Translational GTPases

    Author : Vasili Hauryliuk; Måns Ehrenberg; Richard Buckingham; Uppsala universitet; []
    Keywords : Molecular biology; translation; GTPase; EF-G; eRF3; Molekylärbiologi;

    Abstract : Protein biosynthesis is a core process in all living organisms. Assembly of the protein chain from aminoacids is catalysed by the ribosome, ancient and extremely complex macromolecular machine. READ MORE

  5. 5. Removal and Replacement of Ribosomal Proteins : Effects on Bacterial Fitness and Ribosome Function

    Author : Christina Tobin; Dan I. Andersson; Richard Buckingham; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; MEDICAL AND HEALTH SCIENCES; ribosome; protein synthesis; ribosomal proteins; translation initiation; ribosome biogenesis; fitness costs; compensatory evolution; horizontal gene transfer; Microbiology; Mikrobiologi; Biochemistry; Biokemi; Mikrobiologi; Microbiology;

    Abstract : Protein synthesis is a complex process performed by sophisticated cellular particles known as ribosomes. Although RNA constitutes the major structural and functional component, ribosomes from all kingdoms contain an extensive array of proteins with largely undefined functional roles. READ MORE