Search for dissertations about: "Richard Lundmark"

Showing result 1 - 5 of 7 swedish dissertations containing the words Richard Lundmark.

  1. 1. Sorting nexin 9 in clathrin-mediated endocytosis

    University dissertation from Umeå : Medicinsk biokemi och biofysik

    Author : Richard Lundmark; Sven Carlsson; Elizabeth Smythe; [2004]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; sorting nexin; dynamin; clathrin; endocytosis; human; adaptor protein complexes; Cell- och molekylärbiologi; NATURAL SCIENCES Biology Cell and molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi; medicinsk biokemi; Medical Biochemistry;

    Abstract : Clathrin-mediated endocytosis is a process by which cells can internalise diverse molecules such as nutrients, antigens and signalling-surface receptors. The creation of clathrin-coated vesicles demands interplay between the plasma membrane lipids, cargo molecules and the proteins that build up the coat. READ MORE

  2. 2. Regulation of GRAF1 membrane sculpting function during cell movement

    University dissertation from Umeå : Umeå University

    Author : Monika K. Francis; Richard Lundmark; Pekka Lappalainen; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocytosis; migration; polarisation; tension; CLIC GEEC; GRAF1; Rho GTPase; Cdc42; Rab8; medicinsk biokemi; Medical Biochemistry;

    Abstract : All eukaryotic cells rely on endocytic events to satisfy a constant need for nutrient and fluid uptake from their surroundings. Endocytosis-dependent turnover of cell surface constituents also serves to control signal transduction and establish morphological changes in response to extracellular stimuli. READ MORE

  3. 3. Regulation of assembly and cell surface dynamics of caveolae

    University dissertation from Umeå : Umeå University

    Author : Jagan Mohan; Richard Lundmark; Oleg Shupliakov; [2016]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; medicinsk biokemi; Medical Biochemistry;

    Abstract : A typical mammalian cell plasma membrane displays a high level of plasticity counter balanced with stability. The plasma membrane show various kinds of invaginations to meet physiological demands of the cells such as nutrient uptake, receptor signaling etc. An example of one such invagination observed in many cell types is “Caveola”. READ MORE

  4. 4. Caveolae associated proteins and how they effect caveolae dynamics

    University dissertation from Umeå : Umeå universitet

    Author : Björn Morén; Richard Lundmark; Volker Haucke; [2014]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Caveolae; caveolin; EHD2; cavin; microdomain; microscopy; TIRF; AFM; medicinsk biokemi; Medical Biochemistry;

    Abstract : Caveolae are a type of invaginated membrane domain that has been shown to be involved in several disease states, including lipodystrophy, muscular dystrophies and cancer. Several of these diseases are caused by the lack of caveolae or caveolae-related signaling deficiencies in the tissues in which the caveolar domain are abundant such as lung, adipose, muscle and their related endothelial cells. READ MORE

  5. 5. Pathogen entry mechanisms and endocytic responses to plasma membrane damage

    University dissertation from Umeå : Umeå universitet

    Author : Lars Nygård Skalman; Richard Lundmark; Kristian Riesbeck; [2017]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Endocytosis; plasma membrane; pathogens; virus; bacterial membrane vesicles; Helicobacter pylori; adenovirus 37; listeriolysin O; pore-forming toxins; membrane repair;

    Abstract : Endocytosis is a fundamental cellular process by which cells transport material from the outside to the inside of the cell through the formation of membrane invaginations that bud off from the plasma membrane. This process is important for nutrient uptake, regulating cell surface receptors and the overall plasma membrane composition. READ MORE