Search for dissertations about: "Richard Lundmark"

Showing result 1 - 5 of 9 swedish dissertations containing the words Richard Lundmark.

  2. 1. Sorting nexin 9 in clathrin-mediated endocytosis

    Author : Richard Lundmark; Sven Carlsson; Elizabeth Smythe; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; sorting nexin; dynamin; clathrin; endocytosis; human; adaptor protein complexes; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; medicinsk biokemi; Medical Biochemistry;

    Abstract : Clathrin-mediated endocytosis is a process by which cells can internalise diverse molecules such as nutrients, antigens and signalling-surface receptors. The creation of clathrin-coated vesicles demands interplay between the plasma membrane lipids, cargo molecules and the proteins that build up the coat. READ MORE

  4. 2. Regulation of GRAF1 membrane sculpting function during cell movement

    Author : Monika K. Francis; Richard Lundmark; Pekka Lappalainen; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocytosis; migration; polarisation; tension; CLIC GEEC; GRAF1; Rho GTPase; Cdc42; Rab8; medicinsk biokemi; Medical Biochemistry;

    Abstract : All eukaryotic cells rely on endocytic events to satisfy a constant need for nutrient and fluid uptake from their surroundings. Endocytosis-dependent turnover of cell surface constituents also serves to control signal transduction and establish morphological changes in response to extracellular stimuli. READ MORE

  5. 3. Non-canonical ATG8 conjugation in ESCRT-driven membrane remodeling processes

    Author : Anastasia Knyazeva; Yao-Wen Wu; Richard Lundmark; Sascha Martens; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ATG8 conjugation; Endosomal Sorting Complex Required for Transport; membrane remodeling; chemical genetics;

    Abstract : ATG8 family proteins have the unique ability to conjugate to membrane lipids. Initially identified as a hallmark of autophagy, ATG8 lipidation is emerging as an important regulator of a growing list of non-degradative cellular functions. READ MORE

  6. 4. Macromolecular organization of the chikungunya virus replication organelle

    Author : Timothée Laurent; Lars-Anders Carlson; Richard Lundmark; Alex Evilevitch; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : The chikungunya virus is a positive-sense RNA virus responsible for the crippling chikungunya fever. It is transmitted through the bites of two species of mosquitoes: Aedes aegypti and Aedes albopictus. READ MORE

  7. 5. Regulation of assembly and cell surface dynamics of caveolae

    Author : Jagan Mohan; Richard Lundmark; Oleg Shupliakov; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; medicinsk biokemi; Medical Biochemistry;

    Abstract : A typical mammalian cell plasma membrane displays a high level of plasticity counter balanced with stability. The plasma membrane show various kinds of invaginations to meet physiological demands of the cells such as nutrient uptake, receptor signaling etc. An example of one such invagination observed in many cell types is “Caveola”. READ MORE