Search for dissertations about: "Rickard Malmström"

Found 2 swedish dissertations containing the words Rickard Malmström.

2. 1. Neuropeptide Y Y1 receptor mechanisms in sympathetic vascular control

   Author : Rickard E Malmström; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Sympathetic vasoconstriction; neuropeptide Y1 Y; receptor antagonists; BIBP 3226; SR 120107A; ischaemia; pig.;

   Abstract : It was demonstrated that the Y1 receptor was the predominant vascular neuropeptide Y (NPY) receptor in pig kidney and hind limb as exogenous and endogenous NPY evoked vasoconstrictor responses that were almost or totally abolished by the selective non-peptide Y1 receptor antagonist, BIBP 3226. Furthermore, renal vasoconstriction was evoked by NPY and a peptide Y1 agonist, but not by a Y 2 agonist, and these responses were strongly reduced by another non-peptide Y, receptor antagonist, SR 120107A. READ MORE

4. 2. Functional Studies of the Neuropeptide Y System : Receptor-Ligand Interaction and Regulation of Food Intake

   Author : Helena Åkerberg; Dan Larhammar; Rickard Malmström; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropeptide Y; G-protein coupled receptor GPCR ; site-directed mutagenesis; pancreatic polypeptide; food intake; dog; Pharmacology; Farmakologi;

   Abstract : The members of the mammalian neuropeptide Y family, i.e. the peptides neuropeptide Y (NPY), peptide YY (PYY) and pancreatic polypeptide (PP), are all involved in regulation of food intake. In human and most other mammals they act via receptors Y1, Y2, Y4 and Y5. READ MORE