Search for dissertations about: "Riikka Kokkola"

Found 1 swedish dissertation containing the words Riikka Kokkola.

2. 1. HMBG1 as a proinflammatory mediator in arthritis

   Author : Riikka Kokkola; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Proinflammatory cytokines are central in the pathogenesis of chronic arthritis and a new generation of therapeutics blocking TNF or IL-1 has improved outcome for many patients with inflammatory joint diseases. This thesis addresses the role of HMGB1 (High Mobility Group Box Chromosomal protein 1) in inflammation and as a potential novel therapeutic target molecule in arthritis. READ MORE