Search for dissertations about: "Ro 52kD"

Found 2 swedish dissertations containing the words Ro 52kD.

  2. 1. RNA-protein complexes as autoantigens : cell and molecular biology of Ro/SSA and disease associations of anti-Ro/SSA antibodies

    Author : Nader Pourmand; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Ro SSA; Ro 52kD; Ro 60kD; p40phox; Ig classes; systemic lupus erythematosus; Sjögren s syndrome; autoantibodies; immunoblotting;

    Abstract : Autoantibodies to the Ro/SSA and La/SSB antigens are present in sera from patients with Sjögren's syndrome (SS) and systemic lupus erythematosus (SLE). The Ro/SSA autoantigen consists of a 52kD and a 60kD protein, complexed with one of four small RNAs. The La protein can also associate with the complex. READ MORE

  4. 2. Immune responses to the Ro and La autoantigens

    Author : Pia Tengnér; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Sjögren s syndrome; systemic lupus erythematosus; Ro SS-A; La SS-B;

    Abstract : Sjögren's syndrome (SS) and systemic lupus erythematosus (SLE) are rheumatic diseases characterized by autoantibody production directed to the Ro/SS-A and La/SS-B autoantigens. The Ro/SS-A is a complex of one of four small RNAs denoted hY RNAs, and three proteins; Ro 60kD, Ro 52kD and La. READ MORE