Search for dissertations about: "Robert Bränström"

Found 4 swedish dissertations containing the words Robert Bränström.

  2. 1. Metabolic signals and the ATP-sensitive potassium channel in the pancreatic beta-cell

    Author : Robert Bränström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ATP-regulated K channel; pancreatic [beta]-cell oscillations; [alpha]-ketoisocaproate; long chain acyl-CoA esters; Kir6.2 SUR1 structure-function.;

    Abstract : ATP-sensitive K+ (KATP) channels are widely distributed in a variety of tissues and cell types. KATP channels are comprised of two subunits, a pore forming subunit (Kir6.x) and a regulatory sulfonylurea receptor (SURx). Both subunits are required for fully functional channels. READ MORE

  4. 2. Molecular studies of endocrine tumors : Insights from genetics and epigenetics

    Author : Samuel Backman; Per Hellman; Peter Stålberg; Olov Norlén; Robert Bränström; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroendocrine tumors; Carcinoid; Pheochromocytoma; Aldosterone; Cancer; MEN1; Multiple endocrine neoplasia; Medicinsk vetenskap; Medical Science;

    Abstract : Endocrine tumors may be benign or malignant and may occur in any of the hormone producing tissues. They share several biological characteristics, including a low mutation-burden, and may co-occur in several hereditary tumor syndromes. The aim of this thesis was to identify genetic and epigenetic aberrations in endocrine tumors. READ MORE

  5. 3. Tumour stromal and demographical factors affecting the metastatic aggressiveness of small differentiated papillary thyroid cancers in Sweden

    Author : Haytham Bayadsi; Joakim Hennings; Malin Sund; Robert Bränström; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Papillary thyroid cancer; Tumour stroma; Geographic information system; Register; Surgery; kirurgi;

    Abstract : Background: The incidence of papillary thyroid cancer (PTC) has been increasing over the recent decades, especially that of small papillary thyroid cancers (sPTCs) (≤ 20mm in size). sPTCs are generally classified as low risk cancers with a very favourable diagnosis, yet some of these cancers still cause locoregional and distant metastasis, recurrence and even death. READ MORE

  6. 4. Small Intestinal Neuroendocrine Tumors : Clinical Studies, Novel Serum Biomarkers and Sensitivity to Cytotoxic and Targeted Agents

    Author : Kosmas Daskalakis; Peter Stålberg; Per Hellman; Olov Norlén; Robert Bränström; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SI-NET; fibrosis; locoregional surgery; liver transplantation; biomarkers; ex vivo sensitivity.;

    Abstract : Small Intestinal Neuroendocrine Tumors (SI-NETs) are indolent neoplasms with an increasing annual incidence of approximately 1/100 000 people. They are often diagnosed at a late stage, restricting treatment efficacy. READ MORE