Search for dissertations about: "Roland Hartmann"
Found 2 swedish dissertations containing the words Roland Hartmann.
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1. Lead(II) as a Tool for Probing RNA Structure in vivo
Abstract : Chemical modification and limited enzymatic hydrolysis are powerful methods to obtain detailed information on the structure and dynamics of RNAs in solution. In the work presented here I have taken advantage of the properties of the divalent metal ion lead(II) to establish it as a new probe for investigating the structure of RNA in vivo. READ MORE
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2. Investigation of RNase P active site residues and catalytic domain interaction
Abstract : RNase P is an essential endoribonuclease responsible for the maturation of the tRNA 5’end. The RNase P family encompasses the ribozyme based, RNase P RNP, and proteinaceous RNase P (PRORP). The ribozyme based RNase P is widely distributed in most species while PRORP has so far mainly been found in some eukaryotic cells. READ MORE