Search for dissertations about: "Rolf Larsson"
Showing result 16 - 20 of 51 swedish dissertations containing the words Rolf Larsson.
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16. Studies of New Signal Transduction Modulators in Acute Myeloid Leukemia
Abstract : Acute myeloid leukemia (AML) is a life-threatening malignant disorder with dismal prognosis. AML is characterized by frequent genetic changes involving tyrosine kinases, normally acting as important mediators in many basic cellular processes. READ MORE
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17. Imaging methods for haemostasis research
Abstract : Blood is a vital part of the human physiology; a transport system that brings nutrients and oxygen to sustain living cells and simultaneously facilitates the removal of carbon dioxide and other waste products from the body. To assure the continuity of these functions, it is of uttermost importance to keep the flowing blood inside the vascular system at any cost. READ MORE
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18. Why did the Riksbank miss its target? A Swedish Phillips curve
Abstract : .... READ MORE
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19. Preclinical Development of New Alkylating Oligopeptides for Cancer Therapy
Abstract : Oligopeptides can be used to carry cytotoxic agents in cancer chemotherapy, using tumour-associated proteins as the molecular target for selectivity. During the seventies and eighties Peptichemio, a cocktail of six alkylating oligopeptides carrying m-L-sarcolysin, was investigated in a wide variety of human malignancies. READ MORE
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20. Integrating Efficacy and Toxicity in Preclinical Anticancer Drug Development : Methods and Applications
Abstract : Preclinical testing is an important part of cancer drug development. The aim of this thesis was to establish and evaluate preclinical in vitro methods useful in the development of new anticancer drugs. In paper I, the development of non-clonogenic assays (FMCA-GM) using CD34+ stem cells for assessment of haematological toxicity was described. READ MORE