Search for dissertations about: "Rujia Xie"
Found 1 swedish dissertation containing the words Rujia Xie.
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1. Pharmacokinetic aspects of the blood-brain barrier transport and equilibration of opioids studied with microdialysis in rats and mice
Abstract : The blood-brain barrier (BBB) transport and equilibration of opioids with different physico-chemical properties and similar structures - codeine, morphine, morphine3-glucuronide (M3G) and morphine-6-glucuronide (M6G) - were investigated in rats and mice using microdialysis. The influences of active efflux pumps, P-glycoprotein (Pgp) and multidrug resistance protein (MRP1), on the BBB transport of morphine and M3G were studied. READ MORE
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