Search for dissertations about: "S Asp"

Showing result 1 - 5 of 20 swedish dissertations containing the words S Asp.

  1. 1. Downstream functions of the Sty1 MAPK pathway in S. pombe

    University dissertation from Göteborg : University of Gothenburg

    Author : Eva Asp; Göteborgs universitet.; Gothenburg University.; [2007]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; S.pombe; MAPK; Sty1; Mkp1; oxidative stress; translation; mRNA stability;

    Abstract : MAP kinase pathways are involved in the response to environmental changes in eukaryotic cells regulating transcriptional and translational events. In S. READ MORE

  2. 2. In Vitro Studies of Adrenocorticolytic DDT Metabolites, with Special Focus on 3-methylsulfonyl-DDE

    University dissertation from Uppsala, Sweden : Acta Universitatis Upsaliensis

    Author : Vendela Asp; Uppsala universitet.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Toxicity; 3-methylsulfonyl-DDE; CYP; adrenal cortex; metabolic activation; steroid hormones; Y-1; H295R; mitotane; adrenocortical carcinoma; NATURAL SCIENCES Biology Cell and molecular biology Toxicology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Toxikologi; Biologi med inriktning mot ekotoxikologi; Biology with specialization in Environmental Toxicology;

    Abstract : The DDT metabolite 3-methylsulfonyl-DDE (3-MeSO2-DDE) is bioactivated by cytochrome P450 11B1 (CYP11B1) in the adrenal cortex of mice and forms irreversibly bound protein adducts, reduces glucocorticoid secretion, and induces cell death selectively in cortisol-producing adrenocortical cells. 3-MeSO2-DDE has therefore been proposed as a lead compound for an improved adrenocortical carcinoma (ACC) therapy. READ MORE

  3. 3. Impact of chronic kidney disease on the cardiovascular system : studies in non-dialysis patients and healthy people

    University dissertation from Stockholm : Karolinska Institutet, Dept of Molecular Medicine and Surgery

    Author : Anna Asp; Karolinska Institutet.; Karolinska Institutet.; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Background: Cardiac and arterial remodeling and stiffening occur in end-stage renal disease. The presence of cardiovascular (CV) alterations in earlier-stage chronic kidney disease (CKD) is less well studied. READ MORE

  4. 4. The meaing(s) of inclusion in mathematics in student talk Inclusion as a topic when students talk about learning and teaching in mathematics

    University dissertation from Växjö : Linnaeus University Press

    Author : Helena Roos; Linnéuniversitetet.; [2019]
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; inclusion in mathematics; discourse analysis; students´meaning s ; Mathematical Education; Matematikdidaktik;

    Abstract : This thesis contributes to research and practice within the field of specialeducation in mathematics with more knowledge about, and an understandingof, students´ meaning(s) of inclusion in mathematics education. Three researchquestions guide the study: What meaning(s) is/are ascribed, and how isinclusion used, in mathematics education research? What meaning(s) do thestudents ascribe to inclusion in mathematics learning and teaching? And whatframes students´ meaning(s) of inclusion in mathematics learning and teaching?The first part of this study began with a systematic literature review on thenotion of inclusion in mathematics education research, and the search resultedin 1,296 research studies. READ MORE

  5. 5. Functional domains in the Alzheimer�s disease-associated presenilin 1 protein

    University dissertation from Stockholm : Karolinska Institutet, Department of Clinical Neuroscience, Occupational Therapy and Elderly Care Research (NEUROTEC)

    Author : Hanna Laudon; Karolinska Institutet.; Karolinska Institutet.; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Alzheimer's disease (AD), the most common cause of dementia, is neuropathologically characterized by the presence of neurofibrillary tangles and amyloid plaques in the brain. Amyloid plaques are extracellular deposits primarily composed of the amyloid beta-peptide (Abeta). READ MORE