Search for dissertations about: "S Asp"

Showing result 16 - 20 of 21 swedish dissertations containing the words S Asp.

  2. 16. Leukotriene A4 hydrolase : studies of structure-function relationships by site-directed mutagenesis and X-ray crystallography

    Author : Peter C Rudberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Inflammation is the pathophysiological mechanism by which an organism clears and rebuilds a site of infection or injury. It is also the characteristic feature of a multitude of severe diseases, with the potential of afflicting almost any organ system. READ MORE

  4. 17. Studies on global regulators involved in virulence gene expression in Staphylococcus aureus

    Author : Anna Kanth; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Staphylococcus aureus is a leading cause of skin, soft tissue, respiratory and endovascular diseases. Staphylococcal pathogenicity depends on the coordinated action of at least 40 different virulence factors, including cytolytic toxins (hla, hlb, luk) enterotoxins (ent), several proteases (ssp, aur, scp) and a large number of cell wall-associated proteins, such as protein A (spa), and fibronectin binding protein (FnBPs). READ MORE

  5. 18. Pharmacological evaluation of the NO/cGMP signalling system

    Author : Anna Asplund Persson; Karl-Erik Andersson; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Platelet activation and inhibition are tightly balanced processes, regulated by various endogenous molecules. In this regard, the endothelium plays a key role in mediating inhibition of platelets by releasing nitric oxide (NO) and cAMP-elevating prostaglandins. READ MORE

  6. 19. Analysis of Complement Deficiency States. With Focus on Molecular Characterization of C4 and Properdin Deficiency

    Author : Gunilla Nordin Fredrikson; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mycology; virology; bacteriology; Complement C4; Complement; Complement Screening; Deficiency; Meningococcal Disease; Properdin; Properdin Expression; Microbiology; Sequencing; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : Complement deficiency is associated with an increased risk for invasive infection and immune complex disease. Screening for identification of complement-deficient patients is essential and a new ELISA-based procedure for detection of complement deficiency is described. READ MORE

  7. 20. Physiology of Escherichia coli in batch and fed-batch cultures with special emphasis on amino acid and glucose metabolism

    Author : Ling Han; KTH; []
    Keywords : escherichia coli; amino acids; glycine; quorum sensing; metabolic switch; metabolite po9ols; carbon balance; outer membrne; lipopolysaccharide; batch culture;

    Abstract : The objective of this work is to better understand themetabolism and physiology ofEscherichiacoli(W3110) in defined medium cultures with thelong-term goal of improving cell yield and recombinant proteinproductivity.The order of amino acid utilization inE. colibatch cultures was investigated in a medium with16 amino acids and glucose. READ MORE