Search for dissertations about: "S-phase"

Showing result 11 - 15 of 140 swedish dissertations containing the word S-phase.

  2. 11. dNTPs : the alphabet of life

    Author : Dinesh Kumar; Andrei Chabes; Britt-Marie Sjöberg; Umeå universitet; []
    Keywords : ribonucleotide reductase; dNTP pools; s-phase checkpoint; mutagenesis; medicinsk biokemi; Medical Biochemistry;

    Abstract : From microscopic bacteria to the giant whale, every single living organism on Earth uses the same language of life: DNA. Deoxyribonucleoside triphosphates––dNTPs (dATP, dTTP, dGTP, and dCTP)––are the building blocks of DNA and are therefore the “alphabet of life”. READ MORE

  4. 12. Long-term survival and prognostic factors in endometrial cancer - a populationbased cohort study

    Author : Teresia Svanvik; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endometrial cancer; relative survival; DNA ploidy; s-phase fraction; p53; socioeconomic inequality; early detection;

    Abstract : Aims: The over-all aims of this thesis were to evaluate the associations between prognostic factors and excess mortality rate, between socioeconomic and immigrant status and incidence rate, in endometrioid (EEC) and non-endometrioid (NEC) endometrial carcinoma. Material and methods: Study I-III were retrospective population-based cohort studies including women resident in a defined geographical area, with endometrial carcinoma. READ MORE

  5. 13. Studies on the antiproliferative action of interferon : effects on proteins synthesized in the G1 and S phase of the cell cycle in 2 anchorage-dependent cell lines

    Author : Dan Lundblad; Erik Lundgren; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Interferon; Glioma; Antiproliferative effect; DNA polymerase; Thymidine kinase; 2 -5 oligo A; Protein synthesis; Two-dimensional electrophorensis; Mouse fibroblasts; C-myc; KI-67 antigen;

    Abstract : Interferons (IFNs) are a class of structurally related proteins first discovered to be produced by virus-infected cells. By now, several other inducing agents have been described. READ MORE

  6. 14. Quantitative cellular methods in the evaluation of prostate cancer

    Author : Naining Wang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : prostate cancer; histopathology; nuclear morphology; DNA ploidy; S-phase fraction; thymidine kinas; Ki-67; cell proliferation; fluorescence cytometry; tissue PSA; prognosis;

    Abstract : The distinction between those prostate cancers rapidly progressing and leading to death and those with little likelihood of causing death in cancer is a major goal in current prostate cancer research. Morphological tumor characteristics at present are the basis for evaluation of the prognosis of the disease. READ MORE

  7. 15. Clinical fluorescence cytometry : improvements to preparation methods and instrumentation

    Author : Thomas Heiden; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Fluorescence analysis; flow cytometry; image cytometry; DNA ploidy; proliferation; apoptosis; paraffin-embedded tissues; fresh tissues; S-phase fraction; debris; aggregates; spectral overlap; wavelength switching;

    Abstract : Fluorescence cytometry, which can be carried out by flow or image cytometry (FCM, ICM), provides a highly sensitive and specific tool for quantitative analysis of cell material. It is emerging from being a pure research method and becoming an important adjunct to clinical practice. To better realize its potential, more research is needed. READ MORE