Search for dissertations about: "S. Toll"
Showing result 1 - 5 of 22 swedish dissertations containing the words S. Toll.
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1. Toll-like receptors (TLRs) and inflammatory bone modeling
Abstract : Patients with inflammatory or infectious conditions such as periodontitis, peri-implantitis, osteomyelitis, rheumatoid arthritis, septic arthritis and loosened joint prosthesis display varying severity of destruction in the adjacent bone tissue. Bone loss in inflammatory diseases is considered a consequence of cytokine induced RANKL and subsequent enhanced osteoclast formation. READ MORE
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2. Actions of Antimicrobial Peptides and Bacterial Components in Inflammation
Abstract : Antimicrobial peptides are evolutionally ancient parts of the innate immune system and their primary role is to protect us from infections. The human cathelicidin-derived antimicrobial peptide, LL-37, not only possesses broad spectrum antimicrobial activities but is also able to bind and neutralize bacterial lipopolysaccharide (LPS), an important trigger of the widespread inflammatory response contributing to septic shock. READ MORE
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3. Role of Neutrophils and Innate Immune Mechanisms in Urinary Tract Infections
Abstract : Urinary tract infections (UTI) are among the most common infections in man. Despite their prevalence, information on the molecular mechanisms defects that explain the increased susceptibility to disease are lacking. READ MORE
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4. Dendritic cell maturation and death during Salmonella infection. Role of pro-inflammatory cytokines and MyD88
Abstract : The costimulatory molecules CD80 and CD86 are required for the ability of dendritic cells (DC) to induce both tolerance and immunity. This thesis investigates the control of CD80/CD86 upregulation in vivo on DC during Salmonella infection. READ MORE
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5. Characterization of host and microbe interactions affecting adherence, clearance and systemic spread of S. pneumoniae
Abstract : Streptococcus pneumoniae (the pneumococcus) mainly gives rise to diseases of the respiratory tract, such as pneumonia, acute otitis media and sinusitis, but it also causes severe invasive diseases, such as meningitis and sepsis. The pneumococcus accounts for approximately two million deaths world-wide every year, the majority of which are children in developing countries. READ MORE