Search for dissertations about: "S100A4"

Showing result 1 - 5 of 6 swedish dissertations containing the word S100A4.

  2. 1. The role of S100A4 protein as a regulator of inflammation and bone metabolism in experimental arthritis

    Author : Li Bian; Göteborgs universitet; []
    Keywords : S100A4; arthritis; animal model; bone; inflammation;

    Abstract : S100A4 belongs to the family of calcium-binding S100 proteins and modulates cell proliferation, cytoskeletal rearrangement, cell motility, and angiogenesis. Increased levels of S100A4 expression correlate with high incidence of metastasis of cancers. READ MORE

  4. 2. Conformational Flexibility in Protein Function: Dynamics of S100A4, Photosynthetic Reaction Centre and the Prenylating Enzymes UbiA and MenA

    Author : Annette Duelli; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Structural Biology;

    Abstract : Proteins are the most versatile macromolecules and they are essentially involved in the biological processes throughout all living organisms. The three dimensional structure of proteins and their dynamical properties underlie their biological function and knowledge about protein structure and dynamics contributes to a detailed understanding of biochemical processes. READ MORE

  5. 3. S100A9 in inflammation

    Author : Zhifei He; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; S100A9; inflammation; oxyclozanide; CD14;

    Abstract : S100A9 is a small (13 kD) cytosolic calcium-binding protein. The protein is mainly expressed in neutrophils and monocytes in human but can also be expressed in other cell types under inflammatory conditions. S100A9 is normally co-expressed with S100A8 and forms S100A8/S100A9 heterodimers. READ MORE

  6. 4. Challenges in the management of urothelial cancer : novel treatment, evaluation of biomarkers, and imaging techniques

    Author : Carl-Henrik Shah; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Urothelial cancer (UC) is the most common malignancy found in the urinary tract. The global annual incidence is approximately 430 000 new cases (Sweden: 3 200 new cases). Approximately one in four new UC patients being diagnosed has muscle-invasive disease. READ MORE

  7. 5. Characterizing cancer cell signaling at the protein level : from targeted to proteome and phosphoproteome­‐wide analyses

    Author : Elena Panizza; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Proteins are the effectors of cellular functions and the constituting elements of cellular signaling cascades. The ability to analyze the abundances and the dynamics of proteins is central to dissect cellular signaling and its effects on cell physiology. READ MORE